{"id":262,"date":"2025-12-31T11:13:24","date_gmt":"2025-12-31T17:13:24","guid":{"rendered":""},"modified":"2026-08-30T21:26:54","modified_gmt":"2026-08-31T03:26:54","slug":"glossary-nnmt-inhibitors","status":"publish","type":"page","link":"https:\/\/portaltowellness.net\/es\/glossary-nnmt-inhibitors\/","title":{"rendered":"Glosario: Inhibidores de NNMT"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><h3>\u00bfQu\u00e9 son los inhibidores de NNMT?<\/h3>\n<p>La nicotinamida N-metiltransferasa (NNMT) es una enzima que metila la nicotinamida, influyendo en las v\u00edas de recuperaci\u00f3n del NAD+ y en el metabolismo celular. Los inhibidores de NNMT son compuestos que bloquean la actividad de esta enzima, lo que permite a los investigadores estudiar c\u00f3mo la metilaci\u00f3n alterada afecta el balance energ\u00e9tico, la tasa metab\u00f3lica y la se\u00f1alizaci\u00f3n celular.<\/p>\n<h3>Aplicaciones en investigaci\u00f3n<\/h3>\n<ul>\n<li>Investigaci\u00f3n de la regulaci\u00f3n de la s\u00edntesis de NAD+ y el metabolismo de la nicotinamida.<\/li>\n<li>Modelado de trastornos metab\u00f3licos, obesidad y resistencia a la insulina.<\/li>\n<li>Exploraci\u00f3n de los mecanismos del envejecimiento, la actividad de las sirtuinas y la funci\u00f3n mitocondrial.<\/li>\n<\/ul>\n<h3>Solo para uso en investigaci\u00f3n<\/h3>\n<p>Esta entrada del glosario se proporciona con fines educativos y de discusi\u00f3n cient\u00edfica. Los compuestos mencionados est\u00e1n destinados exclusivamente a la investigaci\u00f3n en laboratorio y no son para consumo humano ni animal. Esta informaci\u00f3n no constituye asesoramiento m\u00e9dico.<\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>Glosario: Inhibidores de NNMT<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-262","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/pages\/262","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=262"}],"version-history":[{"count":3,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/pages\/262\/revisions"}],"predecessor-version":[{"id":7166,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/pages\/262\/revisions\/7166"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=262"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}