{"id":120,"date":"2025-11-03T01:51:50","date_gmt":"2025-11-03T07:51:50","guid":{"rendered":"https:\/\/portaltowellness.net\/?post_type=product&#038;p=120"},"modified":"2026-09-16T09:58:25","modified_gmt":"2026-09-16T14:58:25","slug":"mt-ii","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/mt-ii\/","title":{"rendered":"MT-II \u2013 10mg\/vial (Solo para uso en investigaci\u00f3n)"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation><h2>Descripci\u00f3n general<\/h2>\n<p>Melanotan II (MT-II) es un an\u00e1logo heptapept\u00eddico c\u00edclico sint\u00e9tico de la hormona estimulante de melanocitos alfa (\u03b1-MSH) con actividad agonista amplia y no selectiva sobre los receptores de melanocortina, abarcando los subtipos MC1R al MC5R. Desarrollado originalmente en la Universidad de Arizona como parte de un programa de investigaci\u00f3n para identificar agentes de bronceado sin exposici\u00f3n solar, el perfil de investigaci\u00f3n de Melanotan II se ha expandido hacia la farmacolog\u00eda de receptores de melanocortina, la investigaci\u00f3n conductual del sistema nervioso central, la biolog\u00eda metab\u00f3lica y los estudios cardiovasculares. Su compuesto estructural de origen, PT-141 (Bremelanotida), fue derivado de MT-II con modificaciones orientadas a mejorar su tolerabilidad, lo que ofrece un par natural de farmacolog\u00eda comparativa para la investigaci\u00f3n de receptores de melanocortina.<\/p>\n<h2>Qu\u00e9 es<\/h2>\n<p>Melanotan II es un heptap\u00e9ptido c\u00edclico de tipo lactama con la secuencia Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH\u2082, f\u00f3rmula molecular C\u2085\u2080H\u2086\u2089N\u2081\u2085O\u2089, PM aproximado de 1,024.18 Da, n\u00famero CAS 121062-08-6. Su amplio perfil de activaci\u00f3n de receptores de melanocortina (MC1R-MC5R) lo distingue de PT-141 (que es m\u00e1s selectivo para MC3R\/MC4R) y de la \u03b1-MSH natural. La ciclizaci\u00f3n y la sustituci\u00f3n con Nle le confieren una estabilidad metab\u00f3lica superior a la de los an\u00e1logos lineales de \u03b1-MSH.<\/p>\n<h2>Principales aplicaciones de investigaci\u00f3n<\/h2>\n<ul>\n<li>Investigaci\u00f3n de farmacolog\u00eda y selectividad de receptores de melanocortina de amplio espectro (MC1R\u2013MC5R)<\/li>\n<li>Estudios de pigmentaci\u00f3n de melanocitos, activaci\u00f3n de MC1R y biolog\u00eda de la melanog\u00e9nesis<\/li>\n<li>Investigaci\u00f3n de v\u00edas del SNC a trav\u00e9s de MC3R y MC4R \u2014 estudios sobre apetito, activaci\u00f3n y circuitos de recompensa<\/li>\n<li>Farmacolog\u00eda comparativa de agonistas de receptores de melanocortina frente a PT-141 (bremelanotida) y \u03b1-MSH<\/li>\n<li>Investigaci\u00f3n cardiovascular \u2014 efectos sobre la presi\u00f3n arterial y el coraz\u00f3n mediados por MC3R\/MC4R<\/li>\n<li>Estudios de la v\u00eda de melanocortina antiinflamatoria mediante activaci\u00f3n perif\u00e9rica de receptores MC<\/li>\n<li>Investigaci\u00f3n de relaciones estructura-actividad (SAR) de an\u00e1logos c\u00edclicos de \u03b1-MSH<\/li>\n<li>Estudios de biolog\u00eda de receptores tisulares perif\u00e9ricos MC4R\/MC5R en preparaciones de m\u00fasculo liso<\/li>\n<\/ul>\n<h2>Especificaciones t\u00e9cnicas<\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong>Estructura<\/strong><\/td>\n<td>Heptap\u00e9ptido c\u00edclico de tipo lactama<\/td>\n<\/tr>\n<tr>\n<td><strong>F\u00f3rmula molecular<\/strong><\/td>\n<td>C\u2085\u2080H\u2086\u2089N\u2081\u2085O\u2089<\/td>\n<\/tr>\n<tr>\n<td><strong>Peso molecular<\/strong><\/td>\n<td>~1,024.18 Da<\/td>\n<\/tr>\n<tr>\n<td><strong>N\u00famero CAS<\/strong><\/td>\n<td>121062-08-6<\/td>\n<\/tr>\n<tr>\n<td><strong>Perfil de receptor<\/strong><\/td>\n<td>Agonista amplio MC1R\u2013MC5R<\/td>\n<\/tr>\n<tr>\n<td><strong>Pureza<\/strong><\/td>\n<td>\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr>\n<td><strong>Forma<\/strong><\/td>\n<td>Polvo liofilizado<\/td>\n<\/tr>\n<tr>\n<td><strong>Tama\u00f1o del vial<\/strong><\/td>\n<td>10mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><em>Solo para uso en investigaci\u00f3n de laboratorio. No est\u00e1 destinado a uso humano ni veterinario, ni al diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ninguna agencia reguladora. Debe ser manipulado por personal de investigaci\u00f3n calificado en un entorno de laboratorio que cumpla con la normativa aplicable.<\/em><\/p>\n<p style=\"margin-top:20px;padding:14px 18px;background:#f0f6fa;border-left:4px solid #c9a44d;border-radius:0 4px 4px 0;font-size:0.9rem;line-height:1.5\">\u00bfNo sabes qu\u00e9 compuestos se adaptan a tu investigaci\u00f3n? <a href=\"https:\/\/portaltowellness.net\/research\/\" style=\"color:#0c2b3a;font-weight:700;text-decoration:none\">Explora el Centro de Investigaci\u00f3n \u2192<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>Melanotan II, un agonista sint\u00e9tico de los receptores de melanocortina (MC1R\u2013MC4R) estudiado en farmacolog\u00eda de receptores de melanocortina. Suministrado \u00fanicamente para investigaci\u00f3n de laboratorio e identificaci\u00f3n.<\/p>","protected":false},"featured_media":1109,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[35],"product_cat":[520,521],"product_tag":[429,491,430,492],"class_list":["post-120","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-metabolic-research","product_cat-mitochondrial-longevity","product_tag-injectable","product_tag-melanocortin","product_tag-research","product_tag-tanning","pa_is_restricted_by_app-58","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/120","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=120"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/1109"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=120"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=120"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=120"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=120"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}