{"id":123,"date":"2025-11-03T01:52:15","date_gmt":"2025-11-03T07:52:15","guid":{"rendered":"https:\/\/portaltowellness.net\/?post_type=product&#038;p=123"},"modified":"2026-10-09T09:24:33","modified_gmt":"2026-10-09T14:24:33","slug":"ss-31","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/ss-31\/","title":{"rendered":"SS-31 (Elamipretide) \u2013 50mg\/vial \u2014 Solo para uso en investigaci\u00f3n"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><p><!-- wp:html --><\/p>\n<p><style>.ptw-product-research-link{background:#f6f3ec;border:1px solid #e0d9c8;border-left:4px solid #8a7a4d;border-radius:8px;padding:14px 18px;margin:16px 0 20px;font-size:15px;}.ptw-product-research-link__label{display:block;font-size:11px;font-weight:700;letter-spacing:.08em;text-transform:uppercase;color:#8a7a4d;margin-bottom:6px;}.ptw-product-research-link__link{display:block;color:#1a2b4c;font-weight:600;text-decoration:underline;margin-top:3px;}<\/style>\n<\/p>\n<p><!-- \/wp:html --><br \/><!-- wp:html --><\/p>\n<div class=\"ptw-product-research-link\"><span class=\"ptw-product-research-link__label\">Respaldado por la investigaci\u00f3n<\/span><a class=\"ptw-product-research-link__link\" href=\"https:\/\/portaltowellness.net\/research\/glp1-adjunct-peptide-research-guide\/\">Leer: Compuestos incret\u00ednicos y del eje de la hormona de crecimiento en la literatura \u2192<\/a><\/div>\n<p><!-- \/wp:html --><\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Descripci\u00f3n general<\/h3>\n<p>SS-31 (P\u00e9ptido de Szeto-Schiller 31, tambi\u00e9n conocido como Elamipretida o MTP-131) es un tetrap\u00e9ptido sint\u00e9tico dirigido a las mitocondrias que se concentra selectivamente en la membrana mitocondrial interna, donde interact\u00faa con la cardiolipina, el fosfol\u00edpido caracter\u00edstico de dicha membrana. Al estabilizar la interacci\u00f3n de la cardiolipina con el citocromo c y el Complejo IV de la cadena de transporte de electrones, SS-31 ha sido estudiado en investigaciones publicadas como herramienta para examinar la integridad de las crestas mitocondriales, la eficiencia de la cadena de transporte de electrones y la generaci\u00f3n de especies reactivas de ox\u00edgeno mitocondriales (mitoROS). Su desarrollo cl\u00ednico como Elamipretida en insuficiencia card\u00edaca y s\u00edndrome de Barth ha generado una extensa literatura farmacol\u00f3gica publicada.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Qu\u00e9 es<\/h3>\n<p>SS-31 es un tetrap\u00e9ptido sint\u00e9tico con la secuencia D-Arg-Dmt-Lys-Phe-NH\u2082 (Dmt = 2'6'-dimetiltirosina), con un peso molecular aproximado de 639 Da y n\u00famero CAS 736992-21-5. Los residuos de amino\u00e1cidos arom\u00e1ticos y b\u00e1sicos alternados producen una carga neta positiva que impulsa la acumulaci\u00f3n electrost\u00e1tica en la membrana mitocondrial interna, concentrando el p\u00e9ptido aproximadamente 1000 veces en relaci\u00f3n con el citoplasma, sin depender del potencial de membrana mitocondrial. El anillo fen\u00f3lico rico en electrones del residuo Dmt es responsable de la interacci\u00f3n con la cardiolipina y de la actividad captadora de radicales libres del p\u00e9ptido.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Aplicaciones clave en investigaci\u00f3n<\/h3>\n<ul>\n<li>Investigaci\u00f3n sobre la focalizaci\u00f3n en cardiolipina y estabilizaci\u00f3n de la membrana mitocondrial interna<\/li>\n<li>Estudios sobre la retenci\u00f3n del citocromo c, la eficiencia de la cadena de transporte de electrones y la s\u00edntesis de ATP<\/li>\n<li>Investigaci\u00f3n sobre los mecanismos de supresi\u00f3n de especies reactivas de ox\u00edgeno mitocondriales (mitoROS)<\/li>\n<li>Estudios sobre morfolog\u00eda de las crestas mitocondriales y potencial de membrana<\/li>\n<li>Investigaci\u00f3n en insuficiencia card\u00edaca, lesi\u00f3n por isquemia-reperfusi\u00f3n card\u00edaca y supervivencia de cardiomiocitos<\/li>\n<li>Modelado del s\u00edndrome de Barth y enfermedades por deficiencia de cardiolipina<\/li>\n<li>Investigaci\u00f3n sobre disfunci\u00f3n mitocondrial relacionada con la edad y metabolismo energ\u00e9tico<\/li>\n<li>Modelado precl\u00ednico de isquemia-reperfusi\u00f3n renal y lesi\u00f3n renal aguda<\/li>\n<\/ul>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Especificaciones t\u00e9cnicas<\/h3>\n<table style=\"width: 100%;border-collapse: collapse;margin: 10px 0\">\n<tbody>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Amino\u00e1cidos<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">4 (D-Arg-Dmt-Lys-Phe-NH\u2082)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Peso molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~639 Da<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">N\u00famero CAS<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">736992-21-5<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Tambi\u00e9n conocido como<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Elamipretida; MTP-131; Bendavia<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Mecanismo<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Estabilizador de membrana mitocondrial dirigido a cardiolipina<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Pureza<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Forma<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Polvo liofilizado<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Tama\u00f1o del vial<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">50mg<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Almacenamiento<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u22124 \u00b0F a largo plazo<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"background: #fff8e7;border-top: 2px solid #d4a017;border-bottom: 2px solid #d4a017;padding: 10px;margin-top: 20px\"> <\/p>\n<div style=\"background: #f0f7f7;border-left: 3px solid #2c7a7b;padding: 14px 18px;margin: 16px 0;border-radius: 4px\">\n<p style=\"margin: 0\"><strong>Actualizaci\u00f3n regulatoria \u2014 agosto de 2026:<\/strong> La Elamipretida recibi\u00f3 aprobaci\u00f3n acelerada de la FDA como <strong>Forzinity<\/strong> (elamipretida HCl) el 19 de septiembre de 2025, para una \u00fanica indicaci\u00f3n espec\u00edfica: mejorar la fuerza muscular en pacientes con s\u00edndrome de Barth que pesen al menos 30 kg. Esta es la primera terapia dirigida a mitocondrias en alcanzar la aprobaci\u00f3n de la FDA. Dicha aprobaci\u00f3n no se extiende a la longevidad, el soporte mitocondrial general, la sensibilidad a la insulina ni ning\u00fan otro uso. El SS-31 que se vende en esta p\u00e1gina es un producto de uso en investigaci\u00f3n separado y sin afiliaci\u00f3n \u2014 no cuenta con aprobaci\u00f3n propia de la FDA. Consulta nuestra <a href=\"https:\/\/portaltowellness.net\/research\/mitochondrial-peptide-comparison-ss31-mots-c-nad\/\">comparativa de p\u00e9ptidos mitocondriales<\/a> para m\u00e1s detalles.<\/p>\n<\/div>\n<p>SOLO PARA USO EN INVESTIGACI\u00d3N. No est\u00e1 destinado al consumo humano ni veterinario, ni al diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ning\u00fan organismo regulador. Debe ser manipulado por personal de investigaci\u00f3n calificado en un entorno de laboratorio que cumpla con la normativa aplicable. Estas declaraciones no han sido evaluadas por la Administraci\u00f3n de Alimentos y Medicamentos de los Estados Unidos.<\/p>\n<p style=\"margin-top: 20px;padding: 14px 18px;background: #f0f6fa;border-left: 4px solid #c9a44d;border-radius: 0 4px 4px 0;font-size: 0.9rem;line-height: 1.5\">\u00bfNo sabes qu\u00e9 compuestos se adaptan a tu investigaci\u00f3n? <a style=\"color: #0c2b3a;font-weight: bold;text-decoration: none\" href=\"https:\/\/portaltowellness.net\/research\/\">Explora el Centro de Investigaci\u00f3n \u2192<\/a><\/p>\n<div class=\"ptw-research-library\" style=\"background: #f8f9fa;border-left: 3px solid #2e7d32;padding: 16px 20px;margin-top: 24px;border-radius: 4px\">\n<p style=\"margin: 0 0 8px;font-weight: 600;font-size: 14px;text-transform: uppercase;letter-spacing: .05em;color: #2e7d32\">Biblioteca de investigaci\u00f3n<\/p>\n<ul style=\"margin: 0;padding-left: 20px\">\n<li><a href=\"https:\/\/portaltowellness.net\/research\/sleep-repair-energy-one-system\/\">V\u00edas superpuestas en biolog\u00eda circadiana, de reparaci\u00f3n y mitocondrial<\/a><\/li>\n<li><a href=\"https:\/\/portaltowellness.net\/research\/mitochondrial-peptide-comparison-ss31-mots-c-nad\/\">Comparativa de p\u00e9ptidos mitocondriales: SS-31, MOTS-c y NAD+<\/a><\/li>\n<\/ul>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Elamipretide, un tetrap\u00e9ptido dirigido a las mitocondrias investigado en publicaciones cient\u00edficas por su afinidad de uni\u00f3n a la cardiolipina y sus efectos sobre los complejos de la cadena de transporte de electrones. Suministrado \u00fanicamente para investigaci\u00f3n de laboratorio e identificaci\u00f3n.<\/p>","protected":false},"featured_media":1108,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"Binds cardiolipin in the inner mitochondrial membrane \u2014 a structural mechanism distinct from antioxidant compounds|Studied for mitochondrial membrane potential and ATP production in aged tissue models|Human clinical trial data exists for elamipretide in heart failure|Studied at the level of membrane structure rather than reactive oxygen species scavenging|No hormonal activity or receptor competition documented in the published literature","ptw_coa_url":"","ptw_science_overview":"SS-31 (Szeto-Schiller 31) is a tetrapeptide that concentrates in the inner mitochondrial membrane, where it binds cardiolipin \u2014 a phospholipid critical for cristae architecture and electron transport chain efficiency. Published work describes stabilisation of cardiolipin and reduced cytochrome c dissociation, with effects on the structural integrity of oxidative phosphorylation complexes. Its mechanism is described as membrane-structural rather than ROS-scavenging.","ptw_science_research":"The MMAD clinical trial evaluated exercise capacity and cardiac function with elamipretide (SS-31) in heart failure patients. Animal studies report restoration of mitochondrial membrane potential and ATP production in aged skeletal muscle, kidney protection in ischaemia-reperfusion injury, and cognitive endpoints in neurodegeneration models. The mechanism studied is structural membrane binding rather than ROS scavenging.","ptw_science_stack":"SS-31 and MOTS-c act through different described mechanisms \u2014 membrane structure versus AMPK-mediated metabolic signalling. No adverse interactions with other research compounds are documented in the published literature.","_ptw_batch_number":""},"product_brand":[35],"product_cat":[521],"product_tag":[333,429,48,488,430],"class_list":["post-123","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-mitochondrial-longevity","product_tag-antioxidant","product_tag-injectable","product_tag-longevity-2","product_tag-mitochondrial","product_tag-research","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/123","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=123"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/1108"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=123"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=123"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=123"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=123"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}