{"id":1244,"date":"2026-05-18T17:50:12","date_gmt":"2026-05-18T22:50:12","guid":{"rendered":"https:\/\/portaltowellness.net\/shop\/mitochondrial-energy-bundle\/"},"modified":"2026-10-09T09:39:07","modified_gmt":"2026-10-09T14:39:07","slug":"mitochondrial-energy-bundle","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/mitochondrial-energy-bundle\/","title":{"rendered":"SS-31, MOTS-c y NAD+ Set de Investigaci\u00f3n \u2014 Solo para uso en investigaci\u00f3n"},"content":{"rendered":"
\n
\ud83c\udf81 Combina y Ahorra un 20%<\/strong> \u2014 A\u00f1ade los tres componentes a continuaci\u00f3n y el 20% se aplica autom\u00e1ticamente al finalizar la compra.<\/div>\n

Antecedentes<\/h2>\n

El deterioro mitocondrial es uno de los marcadores del envejecimiento m\u00e1s documentados en la literatura cient\u00edfica. A medida que las mitocondrias pierden eficiencia, la producci\u00f3n de energ\u00eda disminuye, el estr\u00e9s oxidativo aumenta y las c\u00e9lulas adoptan v\u00edas metab\u00f3licas menos eficientes. Los tres compuestos han sido estudiados en distintos puntos de la biolog\u00eda mitocondrial: protecci\u00f3n a nivel de membrana, activaci\u00f3n de la v\u00eda AMPK y se\u00f1alizaci\u00f3n sirtuina dependiente de NAD+.<\/p>\n

Perfiles de los Compuestos<\/h2>\n

SS-31 (Elamipretida) \u2014 Estabilizaci\u00f3n de la Membrana Interna<\/h3>\n

SS-31 se une a la cardiolipina \u2014un fosfol\u00edpido esencial para la integridad de la membrana mitocondrial interna\u2014, preservando la arquitectura de la cadena de transporte de electrones, reduciendo la producci\u00f3n de ROS y restaurando la s\u00edntesis de ATP en mitocondrias envejecidas. Diversos modelos animales han demostrado la reversi\u00f3n de la disfunci\u00f3n mitocondrial asociada al envejecimiento con SS-31.<\/p>\n

MOTS-c \u2014 P\u00e9ptido de Origen Mitocondrial y Activaci\u00f3n de AMPK<\/h3>\n

MOTS-c est\u00e1 codificado en el genoma mitocondrial y act\u00faa como sensor de estr\u00e9s celular, transloc\u00e1ndose al n\u00facleo para activar AMPK y regular el metabolismo de glucosa y l\u00edpidos. En ratones, se ha reportado que MOTS-c modifica la se\u00f1alizaci\u00f3n AMPK y la expresi\u00f3n de genes metab\u00f3licos.<\/p>\n

NAD+ \u2014 El Cofactor de Moneda Energ\u00e9tica<\/h3>\n

NAD+ impulsa el Complejo I de la cadena de transporte de electrones y es el sustrato de SIRT3 \u2014la principal deacetilasa mitocondrial que regula la oxidaci\u00f3n de \u00e1cidos grasos, el ciclo TCA y la detoxificaci\u00f3n de ROS\u2014. Los niveles de NAD+ disminuyen de forma significativa con la edad.<\/p>\n

Aplicaciones de Investigaci\u00f3n<\/h2>\n
    \n
  • Estudios sobre el deterioro mitocondrial asociado al envejecimiento<\/li>\n
  • Investigaci\u00f3n sobre estr\u00e9s oxidativo y producci\u00f3n de ROS<\/li>\n
  • Estudios sobre la v\u00eda AMPK y la flexibilidad metab\u00f3lica<\/li>\n
  • Funci\u00f3n mitocondrial en m\u00fasculo card\u00edaco y esquel\u00e9tico<\/li>\n
  • Estudios sobre mim\u00e9ticos del ejercicio y adaptaci\u00f3n metab\u00f3lica<\/li>\n<\/ul><\/div>","protected":false},"excerpt":{"rendered":"

    Un kit de compuestos estudiados en investigaci\u00f3n mitocondrial y de energ\u00eda celular, suministrados juntos a un costo combinado menor que el de los viales individuales. Solo para uso en investigaci\u00f3n.<\/p>","protected":false},"featured_media":1347,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[],"product_cat":[521,509],"product_tag":[514,518,48,441,513],"class_list":["post-1244","product","type-product","status-publish","has-post-thumbnail","product_cat-mitochondrial-longevity","product_cat-stacks","product_tag-ampk","product_tag-bundle","product_tag-longevity-2","product_tag-mitochondria","product_tag-stack","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-woosb"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/1244","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=1244"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/1347"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=1244"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=1244"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=1244"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=1244"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}