{"id":134,"date":"2025-11-03T01:54:47","date_gmt":"2025-11-03T07:54:47","guid":{"rendered":"https:\/\/portaltowellness.net\/?post_type=product&p=134"},"modified":"2026-10-09T10:10:42","modified_gmt":"2026-10-09T15:10:42","slug":"5-amino-1mq","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/5-amino-1mq\/","title":{"rendered":"5-Amino-1MQ \u2013 50mg\/vial (Solo para Uso en Investigaci\u00f3n)"},"content":{"rendered":"

5-Amino-1MQ \u2013 50mg\/vial<\/h2>\n

5-Amino-1-metilquinolinio (5-Amino-1MQ) es una mol\u00e9cula peque\u00f1a permeable a c\u00e9lulas que act\u00faa como inhibidor de la nicotinamida N-metiltransferasa (NNMT), con un peso molecular de aproximadamente 174 Da. Este vial contiene 50mg de 5-Amino-1MQ de grado investigaci\u00f3n, suministrado como polvo liofilizado para aplicaciones de investigaci\u00f3n precl\u00ednica. La NNMT cataliza la N-metilaci\u00f3n de la nicotinamida utilizando S-adenosil metionina (SAM) como donador del grupo metilo.<\/p>\n

Antecedentes de Investigaci\u00f3n<\/h3>\n

Los investigadores han estudiado el 5-Amino-1MQ como herramienta farmacol\u00f3gica selectiva para explorar la funci\u00f3n de la enzima NNMT. Investigaciones in vitro publicadas han examinado los efectos de los inhibidores de NNMT sobre la disponibilidad de precursores de NAD+, el flujo de la v\u00eda de metilaci\u00f3n y la diferenciaci\u00f3n de adipocitos en modelos de cultivo celular. Investigaciones in vivo con formatos inyectables han examinado la inhibici\u00f3n de NNMT en modelos de roedores, con investigadores midiendo la masa del tejido adiposo, la utilizaci\u00f3n de sustratos metab\u00f3licos y marcadores de expresi\u00f3n g\u00e9nica relevantes para el metabolismo de l\u00edpidos. Estudios farmacocin\u00e9ticos publicados han examinado la biodisponibilidad y distribuci\u00f3n tisular del 5-Amino-1MQ en modelos animales.<\/p>\n

Especificaciones T\u00e9cnicas<\/h3>\n\n\n\n\n\n\n\n\n
Clase de Compuesto<\/strong><\/td>\nMol\u00e9cula peque\u00f1a inhibidora de NNMT<\/td>\n<\/tr>\n
Peso Molecular<\/strong><\/td>\n~174 Da<\/td>\n<\/tr>\n
Pureza<\/strong><\/td>\n\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n
Forma<\/strong><\/td>\nPolvo liofilizado (formulaci\u00f3n de grado inyectable)<\/td>\n<\/tr>\n
Tama\u00f1o del Vial<\/strong><\/td>\n50mg<\/td>\n<\/tr>\n
Almacenamiento<\/strong><\/td>\n\u22124 \u00b0F a largo plazo<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Solo para uso en investigaci\u00f3n. No destinado al consumo humano, diagn\u00f3stico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n.<\/em><\/p>\n

\u00bfNo sabes qu\u00e9 compuestos se adaptan a tu investigaci\u00f3n? Explora el Centro de Investigaci\u00f3n \u2192<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"

5-Amino-1MQ, un inhibidor de mol\u00e9cula peque\u00f1a de la nicotinamida N-metiltransferasa (NNMT), estudiado en investigaci\u00f3n del metabolismo de la nicotinamida y NAD+. Suministrado \u00fanicamente para investigaci\u00f3n de laboratorio e identificaci\u00f3n.<\/p>","protected":false},"featured_media":1077,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[35],"product_cat":[520,521],"product_tag":[429,336,480,430],"class_list":["post-134","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-metabolic-research","product_cat-mitochondrial-longevity","product_tag-injectable","product_tag-metabolic","product_tag-nnmt","product_tag-research","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/134","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=134"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/1077"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=134"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=134"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=134"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=134"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}