{"id":137,"date":"2025-11-03T01:55:08","date_gmt":"2025-11-03T07:55:08","guid":{"rendered":"https:\/\/portaltowellness.net\/?post_type=product&#038;p=137"},"modified":"2026-10-09T09:24:44","modified_gmt":"2026-10-09T14:24:44","slug":"pinealon","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/pinealon\/","title":{"rendered":"Pinealon \u2013 20mg\/vial (Solo para uso en investigaci\u00f3n)"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><h3 style=\"color: #1a7a6e;margin-top: 20px\">Descripci\u00f3n general<\/h3>\n<p>Pinealon es un biorregulador tripept\u00eddico sint\u00e9tico (Glu-Asp-Arg) desarrollado en el Instituto de Biorregulaci\u00f3n y Gerontolog\u00eda de San Petersburgo como parte del programa de investigaci\u00f3n sobre citomedinas \u2014 una clase de biorreguladores pept\u00eddicos cortos derivados de polip\u00e9ptidos espec\u00edficos de tejido, originalmente aislados de extractos de \u00f3rganos. Como biorregulador pept\u00eddico asociado a compuestos de investigaci\u00f3n derivados de la gl\u00e1ndula pineal, Pinealon ha sido estudiado en la literatura publicada en el contexto de la expresi\u00f3n g\u00e9nica neuronal, los mecanismos neuroprotectores, la biolog\u00eda celular retiniana y la investigaci\u00f3n neuroendocrina circadiana, junto con la serie m\u00e1s amplia de biorreguladores pept\u00eddicos de Khavinson.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Qu\u00e9 es<\/h3>\n<p>Pinealon es un trip\u00e9ptido sint\u00e9tico Glu-Asp-Arg con un PM aproximado de 403 Da, n\u00famero CAS 188922-50-1. Al igual que otros biorreguladores pept\u00eddicos de tipo citomedina (Epithal\u00f3n, Timalina, serie Cortexin), se cree que Pinealon act\u00faa mediante mecanismos epigen\u00e9ticos \u2014 interactuando con regiones reguladoras del ADN a trav\u00e9s de interacciones electrost\u00e1ticas con histonas \u2014 en lugar de mediante la uni\u00f3n a receptores convencionales. La investigaci\u00f3n publicada en biolog\u00eda celular ha examinado los efectos de Pinealon sobre marcadores de diferenciaci\u00f3n neuronal, indicadores de da\u00f1o oxidativo al ADN y perfiles de expresi\u00f3n proteica en preparaciones de c\u00e9lulas neuronales y retinianas.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Aplicaciones de investigaci\u00f3n principales<\/h3>\n<ul>\n<li>Investigaci\u00f3n sobre biolog\u00eda de biorreguladores pept\u00eddicos citomedina y regulaci\u00f3n epigen\u00e9tica de la expresi\u00f3n g\u00e9nica<\/li>\n<li>Estudios de marcadores de neuroprotecci\u00f3n y supervivencia neuronal en modelos de estr\u00e9s oxidativo<\/li>\n<li>Investigaci\u00f3n sobre biolog\u00eda de c\u00e9lulas ganglionares de la retina y fotorreceptores<\/li>\n<li>Estudios de biolog\u00eda circadiana y funci\u00f3n de la gl\u00e1ndula pineal<\/li>\n<li>Investigaci\u00f3n sobre la respuesta al da\u00f1o oxidativo del ADN y la v\u00eda de reparaci\u00f3n por escisi\u00f3n de bases<\/li>\n<li>Estudios de marcadores de diferenciaci\u00f3n neuronal y crecimiento de neuritas en sistemas de cultivo celular<\/li>\n<li>Investigaci\u00f3n comparativa sobre biorreguladores pept\u00eddicos de Khavinson (Pinealon vs. Epithal\u00f3n, Cortexin)<\/li>\n<li>Estudios de biolog\u00eda del tejido neurol\u00f3gico asociado al envejecimiento y marcadores de longevidad<\/li>\n<\/ul>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Especificaciones t\u00e9cnicas<\/h3>\n<table style=\"width: 100%;border-collapse: collapse;margin: 10px 0\">\n<tbody>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Amino\u00e1cidos<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">3 (Glu-Asp-Arg)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Peso molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~403 Da<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">N\u00famero CAS<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">188922-50-1<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Clasificaci\u00f3n<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Biorregulador pept\u00eddico citomedina (derivado pineal)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Pureza<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Forma<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Polvo liofilizado<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Tama\u00f1o del vial<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">20mg<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Almacenamiento<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u22124 \u00b0F a largo plazo<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"background: #fff8e7;border-top: 2px solid #d4a017;border-bottom: 2px solid #d4a017;padding: 10px;margin-top: 20px\"><strong>SOLO PARA USO EN INVESTIGACI\u00d3N.<\/strong> No est\u00e1 destinado al consumo humano ni veterinario, ni al diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ning\u00fan organismo regulador. Debe ser manipulado por personal de investigaci\u00f3n calificado en un entorno de laboratorio adecuado. Estas declaraciones no han sido evaluadas por la Administraci\u00f3n de Alimentos y Medicamentos de los Estados Unidos.<\/p>\n<p style=\"margin-top: 20px;padding: 14px 18px;background: #f0f6fa;border-left: 4px solid #c9a44d;border-radius: 0 4px 4px 0;font-size: 0.9rem;line-height: 1.5\">\u00bfNo sabes qu\u00e9 compuestos se adaptan a tu investigaci\u00f3n? <a style=\"color: #0c2b3a;font-weight: bold;text-decoration: none\" href=\"https:\/\/portaltowellness.net\/research\/\">Explora el Hub de Investigaci\u00f3n \u2192<\/a><\/p>\n<p><!-- PTW-RESEARCH-LINKS --><\/p>\n<h3>Investigaci\u00f3n relacionada (educativa)<\/h3>\n<ul>\n<li><a href=\"https:\/\/portaltowellness.net\/research\/semax-selank-pinealon-what-the-research-shows-about-nootropic-peptides\/\">Semax, Selank y Pinealon: lo que muestra la investigaci\u00f3n sobre p\u00e9ptidos nootr\u00f3picos<\/a><\/li>\n<li><a href=\"https:\/\/portaltowellness.net\/research\/sleep-repair-energy-one-system\/\">V\u00edas superpuestas en biolog\u00eda circadiana, de reparaci\u00f3n y mitocondrial<\/a><\/li>\n<\/ul><\/div>","protected":false},"excerpt":{"rendered":"<p>Pinealon (Glu-Asp-Arg), un trip\u00e9ptido sint\u00e9tico estudiado en investigaci\u00f3n de biorreguladores de p\u00e9ptidos cortos y expresi\u00f3n g\u00e9nica neuronal. Suministrado solo para investigaci\u00f3n en laboratorio y prop\u00f3sitos de identificaci\u00f3n.<\/p>","protected":false},"featured_media":1104,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[35],"product_cat":[507,550],"product_tag":[442,429,231,430],"class_list":["post-137","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-neuropeptides","product_cat-hormone-circadian","product_tag-cognitive","product_tag-injectable","product_tag-neuropeptide","product_tag-research","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/137","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=137"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/1104"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=137"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=137"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=137"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=137"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}