{"id":142,"date":"2025-11-03T11:00:15","date_gmt":"2025-11-03T17:00:15","guid":{"rendered":"https:\/\/portaltowellness.net\/?post_type=product&#038;p=142"},"modified":"2026-09-16T06:47:27","modified_gmt":"2026-09-16T11:47:27","slug":"s9-sr9009-10-mg-x-100-tablets-oral","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/s9-sr9009-10-mg-x-100-tablets-oral\/","title":{"rendered":"SR9009 \u2013 10mg \u00d7 100 tabletas (Solo para uso en investigaci\u00f3n)"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><h3 style=\"color: #1a7a6e;margin-top: 20px\">Descripci\u00f3n general<\/h3>\nSR9009 es un agonista sint\u00e9tico de mol\u00e9cula peque\u00f1a de Rev-Erb alfa (NR1D1) y Rev-Erb beta (NR1D2) \u2014 receptores nucleares que funcionan como componentes centrales de la maquinaria del reloj circadiano y reguladores transcripcionales de las redes de genes metab\u00f3licos. Como herramienta farmacol\u00f3gica que permiti\u00f3 la caracterizaci\u00f3n definitiva del papel de Rev-Erb en la programaci\u00f3n metab\u00f3lica, la regulaci\u00f3n del ritmo circadiano y la biog\u00e9nesis mitocondrial, SR9009 ha generado un importante inter\u00e9s en la investigaci\u00f3n publicada. Estudios publicados han examinado los efectos de SR9009 sobre el metabolismo de l\u00edpidos y glucosa, el contenido mitocondrial y el comportamiento circadiano en m\u00faltiples sistemas de modelos de roedores.\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">\u00bfQu\u00e9 es?<\/h3>\nSR9009 es una benzimidazol tioproprilamina sint\u00e9tica con f\u00f3rmula molecular C\u2082\u2083H\u2082\u2086ClN\u2083O\u2083S, PM ~480.0 Da, n\u00famero CAS 1379686-30-2. Act\u00faa como ligando directo de los dominios de uni\u00f3n a ligando de los receptores nucleares Rev-Erb alfa (NR1D1) y Rev-Erb beta (NR1D2), desplazando el complejo co-represor NCoR\/HDAC3 de estos receptores y modificando la actividad transcripcional de los genes diana de Rev-Erb, incluyendo BMAL1, CLOCK, y reguladores metab\u00f3licos como PPAR-gamma, SREBP-1c y PGC-1alfa.\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Aplicaciones clave en investigaci\u00f3n<\/h3>\n<ul>\n \t<li>Investigaci\u00f3n sobre agonismo del receptor Rev-Erb alfa\/beta (NR1D1\/NR1D2) y transcripci\u00f3n del reloj circadiano<\/li>\n \t<li>Estudios de regulaci\u00f3n de BMAL1, CLOCK y la red de genes circadianos<\/li>\n \t<li>Investigaci\u00f3n sobre metabolismo de l\u00edpidos, bios\u00edntesis de colesterol y v\u00edas de \u00e1cidos biliares<\/li>\n \t<li>Estudios sobre homeostasis de glucosa, gluconeog\u00e9nesis hep\u00e1tica y metabolismo del gluc\u00f3geno<\/li>\n \t<li>Investigaci\u00f3n sobre biog\u00e9nesis mitocondrial, metabolismo oxidativo y marcadores de capacidad de ejercicio<\/li>\n \t<li>Estudios sobre adipog\u00e9nesis, diferenciaci\u00f3n de c\u00e9lulas grasas y regulaci\u00f3n de adipocinas<\/li>\n \t<li>Investigaci\u00f3n sobre sincronizaci\u00f3n del ritmo circadiano, arquitectura del sue\u00f1o y cronobiolog\u00eda<\/li>\n \t<li>Estudios sobre programaci\u00f3n metab\u00f3lica del m\u00fasculo esquel\u00e9tico y capacidad oxidativa de fibras<\/li>\n<\/ul>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Especificaciones t\u00e9cnicas<\/h3>\n<table style=\"width: 100%;border-collapse: collapse;margin: 10px 0\">\n<tbody>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Compuesto<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">SR9009<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">F\u00f3rmula molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">C\u2082\u2083H\u2082\u2086ClN\u2083O\u2083S<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Peso molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~480.0 Da<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">N\u00famero CAS<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">1379686-30-2<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Mecanismo<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Agonista del receptor nuclear Rev-Erb \u03b1\/\u03b2<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Pureza<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Presentaci\u00f3n<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Tableta oral (10mg)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Cantidad<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">100 tabletas por frasco<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Almacenamiento<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Lugar fresco y seco, alejado del calor, la humedad y la luz directa<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"background: #fff8e7;border-top: 2px solid #d4a017;border-bottom: 2px solid #d4a017;padding: 10px;margin-top: 20px\"><strong>SOLO PARA USO EN INVESTIGACI\u00d3N.<\/strong> No est\u00e1 destinado al consumo humano ni veterinario, ni para el diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ninguna agencia regulatoria. Debe ser manejado por personal de investigaci\u00f3n calificado en un entorno de laboratorio que cumpla con la normativa aplicable. Estas declaraciones no han sido evaluadas por la Administraci\u00f3n de Alimentos y Medicamentos de los Estados Unidos.<\/p>\n<p style=\"margin-top: 20px;padding: 14px 18px;background: #f0f6fa;border-left: 4px solid #c9a44d;border-radius: 0 4px 4px 0;font-size: 0.9rem;line-height: 1.5\">\u00bfNo sabes qu\u00e9 compuestos se ajustan a tu investigaci\u00f3n? <a style=\"color: #0c2b3a;font-weight: bold;text-decoration: none\" href=\"https:\/\/portaltowellness.net\/research\/\">Explora el Centro de Investigaci\u00f3n \u2192<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>SR9009, un agonista sint\u00e9tico de Rev-Erb\u03b1\/\u03b2 estudiado en investigaci\u00f3n de receptores nucleares circadianos y metab\u00f3licos. Suministrado \u00fanicamente para investigaci\u00f3n en laboratorio y fines de identificaci\u00f3n.<\/p>","protected":false},"featured_media":143,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[35],"product_cat":[520,521],"product_tag":[498,452,336,434,430,497],"class_list":["post-142","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-metabolic-research","product_cat-mitochondrial-longevity","product_tag-circadian","product_tag-exercise-mimetic","product_tag-metabolic","product_tag-oral","product_tag-research","product_tag-rev-erb","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/142","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=142"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/143"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=142"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=142"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=142"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=142"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}