{"id":162,"date":"2025-11-04T12:36:29","date_gmt":"2025-11-04T18:36:29","guid":{"rendered":"https:\/\/portaltowellness.net\/?post_type=product&#038;p=162"},"modified":"2026-10-09T09:15:21","modified_gmt":"2026-10-09T14:15:21","slug":"selank-10mg-vial","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/selank-10mg-vial\/","title":{"rendered":"Selank \u2013 10mg\/vial (Solo para uso en investigaci\u00f3n)"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><h3 style=\"color: #1a7a6e;margin-top: 20px\">Descripci\u00f3n general<\/h3>\n<p>Selank es un heptap\u00e9ptido sint\u00e9tico ansiol\u00edtico desarrollado en el Instituto de Gen\u00e9tica Molecular de la Academia de Ciencias de Rusia. Derivado del tetrap\u00e9ptido inmunomodulador end\u00f3geno tufsina (Thr-Lys-Pro-Arg) con una extensi\u00f3n C-terminal Pro-Gly-Pro para mejorar la estabilidad metab\u00f3lica, Selank ha sido investigado principalmente en neurofarmacolog\u00eda, con trabajos publicados que examinan sus interacciones con los sistemas GABA\u00e9rgico, serotonin\u00e9rgico y dopamin\u00e9rgico, adem\u00e1s de efectos inmunomoduladores y neurotr\u00f3ficos. Cuenta con estatus regulatorio en Rusia como agente ansiol\u00edtico, lo que proporciona una base de investigaci\u00f3n cl\u00ednica y precl\u00ednica.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">\u00bfQu\u00e9 es?<\/h3>\n<p>Selank es un heptap\u00e9ptido sint\u00e9tico con la secuencia Thr-Lys-Pro-Arg-Pro-Gly-Pro, PM aproximado de 751 Da, n\u00famero CAS 129954-34-3. Su estructura se basa en la tufsina (TKPR, un p\u00e9ptido natural derivado del receptor Fc) extendida con Pro-Gly-Pro en el extremo C-terminal. La investigaci\u00f3n publicada ha examinado la modulaci\u00f3n de la neurotransmisi\u00f3n GABA\u00e9rgica por parte de Selank (sin uni\u00f3n directa al receptor GABAA), la expresi\u00f3n de BDNF, la actividad del transportador de serotonina y la estabilidad de las encefalinas mediante inhibici\u00f3n de metaloproteasas.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Principales aplicaciones de investigaci\u00f3n<\/h3>\n<ul>\n<li>Farmacolog\u00eda ansiol\u00edtica e investigaci\u00f3n de modulaci\u00f3n GABA\u00e9rgica sin uni\u00f3n directa al receptor GABAA<\/li>\n<li>Estudios de expresi\u00f3n de BDNF y regulaci\u00f3n de factores neurotr\u00f3ficos en modelos de estr\u00e9s<\/li>\n<li>Investigaci\u00f3n de la actividad del transportador de serotonina (SERT) y modulaci\u00f3n del sistema serotonin\u00e9rgico<\/li>\n<li>Investigaci\u00f3n sobre inhibici\u00f3n de la degradaci\u00f3n de encefalinas y el sistema opioide end\u00f3geno<\/li>\n<li>Investigaci\u00f3n inmunomoduladora \u2014 interacciones con receptores de tufsina y estudios de actividad de macr\u00f3fagos<\/li>\n<li>Respuesta al estr\u00e9s, modulaci\u00f3n del eje HPA y farmacolog\u00eda conductual de la ansiedad en modelos de roedores<\/li>\n<li>Estudios de biomarcadores de funci\u00f3n cognitiva y aprendizaje\/memoria<\/li>\n<li>Investigaci\u00f3n comparativa frente a la clase de benzodiacepinas y otros ansiol\u00edticos GABA\u00e9rgicos<\/li>\n<\/ul>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Especificaciones t\u00e9cnicas<\/h3>\n<table style=\"width: 100%;border-collapse: collapse;margin: 10px 0\">\n<tbody>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Amino\u00e1cidos<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">7 (Thr-Lys-Pro-Arg-Pro-Gly-Pro)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Peso molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~751 Da<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">N\u00famero CAS<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">129954-34-3<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">P\u00e9ptido original<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Tufsina (TKPR) + extensi\u00f3n Pro-Gly-Pro<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Pureza<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Forma<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Polvo liofilizado<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Tama\u00f1o del vial<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">10mg<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Almacenamiento<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u22124 \u00b0F a largo plazo<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"background: #fff8e7;border-top: 2px solid #d4a017;border-bottom: 2px solid #d4a017;padding: 10px;margin-top: 20px\"><strong>SOLO PARA USO EN INVESTIGACI\u00d3N.<\/strong> No est\u00e1 destinado al consumo humano ni veterinario, ni al diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ning\u00fan organismo regulador. Debe ser manipulado por personal de investigaci\u00f3n calificado en un entorno de laboratorio que cumpla con la normativa vigente. Estas declaraciones no han sido evaluadas por la Administraci\u00f3n de Alimentos y Medicamentos de los Estados Unidos.<\/p>\n<p style=\"margin-top: 20px;padding: 14px 18px;background: #f0f6fa;border-left: 4px solid #c9a44d;border-radius: 0 4px 4px 0;font-size: 0.9rem;line-height: 1.5\">\u00bfNo sabes qu\u00e9 compuestos se adaptan a tu investigaci\u00f3n? <a style=\"color: #0c2b3a;font-weight: bold;text-decoration: none\" href=\"https:\/\/portaltowellness.net\/research\/\">Explora el Centro de Investigaci\u00f3n \u2192<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>Un heptap\u00e9ptido sint\u00e9tico derivado de la tuftsin, examinado en la literatura publicada por su interacci\u00f3n con la se\u00f1alizaci\u00f3n GABA\u00e9rgica y monoamin\u00e9rgica en modelos animales. Suministrado \u00fanicamente para investigaci\u00f3n de laboratorio y fines de identificaci\u00f3n.<\/p>","protected":false},"featured_media":1099,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"Studied for anxiolytic activity in preclinical and Russian clinical literature|Modulates GABAergic transmission through a mechanism distinct from benzodiazepines|Reported effects on BDNF and serotonin turnover in preclinical models|Investigated as both an anxiolytic and a nootropic in published literature since the 1990s|Published primarily in Russian-language literature, with limited independent replication","ptw_coa_url":"","ptw_science_overview":"Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic analogue of the endogenous tuftsin peptide, extended with a Pro-Gly-Pro sequence for stability. Published work describes modulation of GABAergic transmission and inhibition of enkephalin-degrading enzymes, at sites distinct from benzodiazepine binding. It is also reported to affect BDNF and TRKB expression, serotonin turnover, and immune signalling. Human evidence outside the Russian-language literature is limited.","ptw_science_research":"Russian clinical trials compared Selank against established anxiolytics on standardised anxiety measures. Cognitive studies report effects on memory consolidation and sustained attention. Immunomodulatory effects \u2014 upregulation of IL-6 and interferon expression \u2014 are reported in the same literature. This body of work has limited independent replication outside Russia.","ptw_science_stack":"Selank and Semax are frequently examined together in the published cognitive literature, acting on different pathways. No compound interactions are documented in that literature.","_ptw_batch_number":""},"product_brand":[35],"product_cat":[507,522],"product_tag":[429,232,430,454],"class_list":["post-162","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-neuropeptides","product_cat-immune-modulators","product_tag-injectable","product_tag-nootropic","product_tag-research","product_tag-stress","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/162","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=162"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/1099"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=162"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=162"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=162"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}