{"id":175,"date":"2026-01-02T02:45:09","date_gmt":"2026-01-02T08:45:09","guid":{"rendered":"https:\/\/portaltowellness.net\/?post_type=product&#038;p=175"},"modified":"2026-10-09T09:26:24","modified_gmt":"2026-10-09T14:26:24","slug":"humanin-10mg-vial","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/humanin-10mg-vial\/","title":{"rendered":"Humanin \u2013 10mg\/vial (Solo para uso en investigaci\u00f3n)"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><h3 style=\"color: #1a7a6e;margin-top: 20px\">Descripci\u00f3n general<\/h3>\n<p>Humanin es un p\u00e9ptido mitocondrial derivado (MDP, por sus siglas en ingl\u00e9s) de 21 amino\u00e1cidos, codificado en el gen del ARN ribos\u00f3mico 16S del genoma mitocondrial. Identificado por primera vez en investigaciones sobre la supervivencia neuronal en modelos de enfermedad de Alzheimer, humanin ha acumulado una amplia literatura publicada que abarca neuroprotecci\u00f3n, biolog\u00eda metab\u00f3lica, investigaci\u00f3n cardiovascular y ciencias de la longevidad. Su descubrimiento abri\u00f3 una nueva frontera de investigaci\u00f3n sobre c\u00f3mo las mitocondrias se comunican con el n\u00facleo, otros org\u00e1nulos y tejidos distantes a trav\u00e9s de se\u00f1ales pept\u00eddicas secretadas.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Qu\u00e9 es<\/h3>\n<p>Humanin (HN) es un p\u00e9ptido de 21 amino\u00e1cidos codificado en el gen ARNr 16S mitocondrial. Peso molecular aproximado de 2,586 Da, n\u00famero CAS 330936-46-4. Act\u00faa a trav\u00e9s de un complejo receptor que involucra CNTFR\/WSX-1\/gp130, e interact\u00faa directamente con prote\u00ednas pro-apopt\u00f3ticas intracelulares como IGFBP-3, Bax y tBid. Humanin se secreta al torrente sangu\u00edneo y se detecta en plasma humano, con niveles que disminuyen con la edad.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Aplicaciones clave en investigaci\u00f3n<\/h3>\n<ul>\n<li>Investigaci\u00f3n de se\u00f1alizaci\u00f3n de p\u00e9ptidos mitocondriales derivados (MDP) y comunicaci\u00f3n mitocondrial-nuclear<\/li>\n<li>Estudios de neuroprotecci\u00f3n e inhibici\u00f3n de la toxicidad del p\u00e9ptido beta-amiloide en modelos precl\u00ednicos de Alzheimer<\/li>\n<li>Investigaci\u00f3n de mecanismos anti-apopt\u00f3ticos \u2014 estudios de interacci\u00f3n con Bax, IGFBP-3 y tBid<\/li>\n<li>Investigaci\u00f3n de la activaci\u00f3n del complejo receptor gp130\/CNTFR\/WSX-1 y la v\u00eda STAT3<\/li>\n<li>Estudios de funci\u00f3n mitocondrial, bioenerg\u00e9tica y biolog\u00eda del envejecimiento<\/li>\n<li>Investigaci\u00f3n sobre sensibilidad a la insulina, metabolismo de la glucosa y supervivencia de c\u00e9lulas beta pancre\u00e1ticas<\/li>\n<li>Protecci\u00f3n cardiovascular \u2014 modelado de apoptosis card\u00edaca y lesi\u00f3n por isquemia-reperfusi\u00f3n<\/li>\n<li>Estudios de correlaci\u00f3n entre la disminuci\u00f3n de MDP relacionada con la edad y marcadores de longevidad<\/li>\n<\/ul>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Especificaciones t\u00e9cnicas<\/h3>\n<table style=\"width: 100%;border-collapse: collapse;margin: 10px 0\">\n<tbody>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Amino\u00e1cidos<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">21<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Peso molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~2,586 Da<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">N\u00famero CAS<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">330936-46-4<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Origen<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">P\u00e9ptido codificado en el gen ARNr 16S mitocondrial<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Mecanismo<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Agonismo de gp130\/CNTFR\/WSX-1; interacciones anti-apopt\u00f3ticas<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Pureza<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Presentaci\u00f3n<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Polvo liofilizado<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Tama\u00f1o del vial<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">10mg<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Almacenamiento<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u22124 \u00b0F a largo plazo<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"background: #fff8e7;border-top: 2px solid #d4a017;border-bottom: 2px solid #d4a017;padding: 10px;margin-top: 20px\"><strong>SOLO PARA USO EN INVESTIGACI\u00d3N.<\/strong> No est\u00e1 destinado al consumo humano ni veterinario, ni al diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ning\u00fan organismo regulador. Debe ser manejado por personal de investigaci\u00f3n calificado en un entorno de laboratorio que cumpla con la normativa aplicable. Estas afirmaciones no han sido evaluadas por la Administraci\u00f3n de Alimentos y Medicamentos de los Estados Unidos.<\/p>\n<p style=\"margin-top: 20px;padding: 14px 18px;background: #f0f6fa;border-left: 4px solid #c9a44d;border-radius: 0 4px 4px 0;font-size: 0.9rem;line-height: 1.5\">\u00bfNo sabes qu\u00e9 compuestos se adaptan mejor a tu investigaci\u00f3n? <a style=\"color: #0c2b3a;font-weight: bold;text-decoration: none\" href=\"https:\/\/portaltowellness.net\/research\/\">Explora el Hub de Investigaci\u00f3n \u2192<\/a><\/p>\n<p><!-- PTW-RESEARCH-LINKS --><\/p>\n<h3>Investigaci\u00f3n relacionada (educativa)<\/h3>\n<ul>\n<li><a href=\"https:\/\/portaltowellness.net\/research\/mitochondrial-peptide-comparison-ss31-mots-c-nad\/\">Comparaci\u00f3n de p\u00e9ptidos mitocondriales: SS-31, MOTS-c y NAD+<\/a><\/li>\n<li><a href=\"https:\/\/portaltowellness.net\/research\/sleep-repair-energy-one-system\/\">V\u00edas superpuestas en biolog\u00eda circadiana, de reparaci\u00f3n y mitocondrial<\/a><\/li>\n<\/ul><\/div>","protected":false},"excerpt":{"rendered":"<p>Humanin, un p\u00e9ptido derivado de las mitocondrias estudiado en investigaci\u00f3n sobre apoptosis y se\u00f1alizaci\u00f3n mitocondrial. Suministrado \u00fanicamente para investigaci\u00f3n en laboratorio y prop\u00f3sitos de identificaci\u00f3n.<\/p>","protected":false},"featured_media":389,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[35],"product_cat":[507,521],"product_tag":[429,48,488,430],"class_list":["post-175","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-neuropeptides","product_cat-mitochondrial-longevity","product_tag-injectable","product_tag-longevity-2","product_tag-mitochondrial","product_tag-research","pa_is_restricted_by_app-58","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/175","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=175"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/389"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=175"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=175"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=175"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=175"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}