{"id":697,"date":"2026-04-26T08:25:52","date_gmt":"2026-04-26T13:25:52","guid":{"rendered":"https:\/\/portaltowellness.net\/shop\/dutasteride\/"},"modified":"2026-10-09T09:27:17","modified_gmt":"2026-10-09T14:27:17","slug":"dutasteride","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/dutasteride\/","title":{"rendered":"Dutasterida \u2013 1mg \u00d7 100 tabletas (Solo para uso en investigaci\u00f3n)"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><h3 style=\"color: #1a7a6e;margin-top: 20px\">Descripci\u00f3n general<\/h3>\n<p>La dutasterida es un inhibidor dual de la 5-alfa reductasa (5-ARI) que bloquea los isoformas tipo 1 y tipo 2 de la enzima responsable de convertir la testosterona en dihidrotestosterona (DHT). Si bien la finasterida (un inhibidor selectivo del tipo 2) ha sido durante mucho tiempo la 5-ARI de referencia en la investigaci\u00f3n de andr\u00f3genos, la inhibici\u00f3n de ambos isoformas por parte de la dutasterida produce una supresi\u00f3n sist\u00e9mica de DHT m\u00e1s completa, lo que la convierte en una valiosa herramienta de investigaci\u00f3n comparativa para diseccionar las contribuciones relativas de la 5-alfa reductasa tipo 1 y tipo 2 a la se\u00f1alizaci\u00f3n androg\u00e9nica en diferentes tejidos.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Qu\u00e9 es<\/h3>\n<p>La dutasterida es un compuesto 4-azasteroide sint\u00e9tico con f\u00f3rmula molecular C\u2082\u2087H\u2083\u2080F\u2086N\u2082O\u2082, PM ~528.53 Da, n\u00famero CAS 164656-23-9. Es un inhibidor competitivo de la 5\u03b1-reductasa tipo 1 (expresada predominantemente en piel, h\u00edgado y cerebro) y tipo 2 (expresada predominantemente en pr\u00f3stata, ves\u00edculas seminales y fol\u00edculos pilosos). Los datos farmacocin\u00e9ticos publicados documentan una semivida plasm\u00e1tica de aproximadamente 5 semanas.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Principales aplicaciones de investigaci\u00f3n<\/h3>\n<ul>\n<li>Farmacolog\u00eda de la inhibici\u00f3n dual de la 5\u03b1-reductasa (tipo 1 y 2) y estudios de selectividad<\/li>\n<li>Supresi\u00f3n de dihidrotestosterona (DHT) e investigaci\u00f3n de la v\u00eda de se\u00f1alizaci\u00f3n androg\u00e9nica<\/li>\n<li>Biolog\u00eda prost\u00e1tica \u2014 modelado de HBP, activaci\u00f3n del receptor de andr\u00f3genos y estudios de tejido prost\u00e1tico<\/li>\n<li>Investigaci\u00f3n mecan\u00edstica de la alopecia androg\u00e9nica y estudios de sensibilidad androg\u00e9nica del fol\u00edculo piloso<\/li>\n<li>Farmacolog\u00eda comparativa frente a finasterida (selectiva del tipo 2) en modelos de supresi\u00f3n de DHT<\/li>\n<li>Metabolismo de neuroesteroides \u2014 investigaci\u00f3n de la v\u00eda de la alopregnanolona y los esteroides neuroactivos<\/li>\n<li>Estudios de la v\u00eda de conversi\u00f3n de andr\u00f3genos suprarrenales (DHEA, androstenediona)<\/li>\n<li>Farmacocin\u00e9tica de 5-ARI de acci\u00f3n prolongada e investigaci\u00f3n de la distribuci\u00f3n tisular de DHT<\/li>\n<\/ul>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Especificaciones t\u00e9cnicas<\/h3>\n<table style=\"width: 100%;border-collapse: collapse;margin: 10px 0\">\n<tbody>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Compuesto<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Dutasterida<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">F\u00f3rmula molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">C\u2082\u2087H\u2083\u2080F\u2086N\u2082O\u2082<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Peso molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~528.53 Da<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">N\u00famero CAS<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">164656-23-9<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Mecanismo<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Inhibidor dual de la 5\u03b1-Reductasa Tipo 1 &amp; 2<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Pureza<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Presentaci\u00f3n<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Tableta oral (1mg)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Cantidad<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">100 tabletas por frasco<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Almacenamiento<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Temperatura ambiente, lejos de la humedad y la luz<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"background: #fff8e7;border-top: 2px solid #d4a017;border-bottom: 2px solid #d4a017;padding: 10px;margin-top: 20px\"><strong>SOLO PARA USO EN INVESTIGACI\u00d3N.<\/strong> No est\u00e1 destinado al consumo humano ni veterinario, ni al diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ning\u00fan organismo regulador. Debe ser manejado por personal de investigaci\u00f3n calificado en un entorno de laboratorio que cumpla con la normativa aplicable. Estas declaraciones no han sido evaluadas por la Administraci\u00f3n de Alimentos y Medicamentos de los Estados Unidos.<\/p>\n<p style=\"margin-top: 20px;padding: 14px 18px;background: #f0f6fa;border-left: 4px solid #c9a44d;border-radius: 0 4px 4px 0;font-size: 0.9rem;line-height: 1.5\">\u00bfNo sabes qu\u00e9 compuestos se adaptan a tu investigaci\u00f3n? <a style=\"color: #0c2b3a;font-weight: bold;text-decoration: none\" href=\"https:\/\/portaltowellness.net\/research\/\">Explora el Centro de Investigaci\u00f3n \u2192<\/a><\/p>\n<div class=\"ptw-research-library\" style=\"background: #f8f9fa;border-left: 3px solid #2e7d32;padding: 16px 20px;margin-top: 24px;border-radius: 4px\">\n<p style=\"margin: 0 0 8px;font-weight: 600;font-size: 14px;text-transform: uppercase;letter-spacing: .05em;color: #2e7d32\">Biblioteca de investigaci\u00f3n<\/p>\n<ul style=\"margin: 0;padding-left: 20px\">\n<li><a href=\"https:\/\/portaltowellness.net\/research\/hair-loss-research-minoxidil-dutasteride\/\">Minoxidil y dutasterida: descripci\u00f3n general del mecanismo<\/a><\/li>\n<\/ul>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Dutasteride, un inhibidor dual de tipo I y tipo II de la 5\u03b1-reductasa utilizado como compuesto de referencia en investigaci\u00f3n sobre se\u00f1alizaci\u00f3n androg\u00e9nica y de DHT. Suministrado exclusivamente para investigaci\u00f3n en laboratorio y fines de identificaci\u00f3n.<\/p>","protected":false},"featured_media":717,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[35],"product_cat":[550,521],"product_tag":[435,434,430],"class_list":["post-697","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-hormone-circadian","product_cat-mitochondrial-longevity","product_tag-dht","product_tag-oral","product_tag-research","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/697","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=697"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/717"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=697"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=697"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=697"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=697"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}