{"id":698,"date":"2026-04-26T08:25:54","date_gmt":"2026-04-26T13:25:54","guid":{"rendered":"https:\/\/portaltowellness.net\/shop\/follistatin-344\/"},"modified":"2026-10-09T09:28:30","modified_gmt":"2026-10-09T14:28:30","slug":"follistatin-344","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/follistatin-344\/","title":{"rendered":"Folistatina 344 \u2013 1mg\/vial (Solo para uso en investigaci\u00f3n)"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><p><!-- wp:html --><\/p>\n<p><style>.ptw-product-research-link{background:#f6f3ec;border:1px solid #e0d9c8;border-left:4px solid #8a7a4d;border-radius:8px;padding:14px 18px;margin:16px 0 20px;font-size:15px;}.ptw-product-research-link__label{display:block;font-size:11px;font-weight:700;letter-spacing:.08em;text-transform:uppercase;color:#8a7a4d;margin-bottom:6px;}.ptw-product-research-link__link{display:block;color:#1a2b4c;font-weight:600;text-decoration:underline;margin-top:3px;}<\/style>\n<\/p>\n<p><!-- \/wp:html --><br \/><!-- wp:html --><\/p>\n<div class=\"ptw-product-research-link\"><span class=\"ptw-product-research-link__label\">Respaldado por la investigaci\u00f3n<\/span><a class=\"ptw-product-research-link__link\" href=\"https:\/\/portaltowellness.net\/research\/glp1-adjunct-peptide-research-guide\/\">Leer: Compuestos incret\u00ednicos y del eje de la hormona de crecimiento en la literatura \u2192<\/a><\/div>\n<p><!-- \/wp:html --><\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Descripci\u00f3n general<\/h3>\n<p>La Follistatina-344 es una isoforma de origen natural de la folistatina, una glicoprote\u00edna secretada codificada por el gen FST que act\u00faa como un potente antagonista end\u00f3geno de la miostatina (GDF-8) y otros miembros de la superfamilia TGF-\u03b2. Al unirse y neutralizar la miostatina \u2014el principal regulador negativo de la masa muscular esquel\u00e9tica\u2014, la Follistatina-344 ha generado un considerable inter\u00e9s en la literatura cient\u00edfica en el campo de la biolog\u00eda muscular, la investigaci\u00f3n de la composici\u00f3n corporal y la endocrinolog\u00eda reproductiva.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Qu\u00e9 es<\/h3>\n<p>La Follistatina-344 es la isoforma de 344 amino\u00e1cidos con uni\u00f3n a heparina de la folistatina humana, producida por splicing alternativo del ARNm del gen FST. PM aproximado de 37\u201345 kDa (glicoprote\u00edna). Contiene tres repeticiones del dominio de folistatina (FSD) que permiten una uni\u00f3n no covalente estrecha a la activina A, la miostatina (GDF-8), GDF-11 y otros ligandos de la familia TGF-\u03b2, secuestr\u00e1ndolos eficazmente de sus receptores.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Principales aplicaciones de investigaci\u00f3n<\/h3>\n<ul>\n<li>Investigaci\u00f3n del mecanismo de uni\u00f3n y neutralizaci\u00f3n de la miostatina (GDF-8)<\/li>\n<li>Estudios de se\u00f1alizaci\u00f3n de hipertrofia del m\u00fasculo esquel\u00e9tico, activaci\u00f3n de c\u00e9lulas sat\u00e9lite y miog\u00e9nesis<\/li>\n<li>Investigaci\u00f3n de las v\u00edas de antagonismo de miembros de la superfamilia TGF-\u03b2 (activina A, GDF-11, BMP)<\/li>\n<li>Estudios comparativos de uni\u00f3n y actividad biol\u00f3gica de isoformas de folistatina (FS-288, FS-315, FS-344)<\/li>\n<li>Investigaci\u00f3n del eje reproductivo \u2014 supresi\u00f3n de FSH, antagonismo de activina y biolog\u00eda ov\u00e1rica<\/li>\n<li>Modelado de enfermedades de desgaste muscular (modelos precl\u00ednicos de caquexia, sarcopenia y distrofia muscular)<\/li>\n<li>Biolog\u00eda del tejido adiposo \u2014 investigaci\u00f3n de la se\u00f1alizaci\u00f3n de miostatina\/activina en la diferenciaci\u00f3n de c\u00e9lulas grasas<\/li>\n<li>Biolog\u00eda \u00f3sea y del cart\u00edlago \u2014 regulaci\u00f3n de BMP-2\/4\/7 e investigaci\u00f3n de la osteog\u00e9nesis<\/li>\n<\/ul>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Especificaciones t\u00e9cnicas<\/h3>\n<table style=\"width: 100%;border-collapse: collapse;margin: 10px 0\">\n<tbody>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Prote\u00edna<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Follistatina-344 (gen FST, isoforma 344)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Amino\u00e1cidos<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">344<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Peso molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~37\u201345 kDa (glicoprote\u00edna)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Objetivo principal<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Miostatina (GDF-8), Activina A, GDF-11<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Mecanismo<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Antagonista de ligandos de la superfamilia TGF-\u03b2<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Pureza<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u226595% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Forma<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Polvo liofilizado<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Tama\u00f1o del vial<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">1mg<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Almacenamiento<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u2212112 \u00b0F a largo plazo; \u22124 \u00b0F a corto plazo; evitar ciclos repetidos de congelaci\u00f3n-descongelaci\u00f3n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"background: #fff8e7;border-top: 2px solid #d4a017;border-bottom: 2px solid #d4a017;padding: 10px;margin-top: 20px\"><strong>SOLO PARA USO EN INVESTIGACI\u00d3N.<\/strong> No destinado al consumo humano o veterinario, ni al diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ning\u00fan organismo regulador. Debe ser manejado por personal de investigaci\u00f3n calificado en un entorno de laboratorio que cumpla con la normativa aplicable. Estas declaraciones no han sido evaluadas por la Administraci\u00f3n de Alimentos y Medicamentos de los Estados Unidos.<\/p>\n<p style=\"margin-top: 20px;padding: 14px 18px;background: #f0f6fa;border-left: 4px solid #c9a44d;border-radius: 0 4px 4px 0;font-size: 0.9rem;line-height: 1.5\">\u00bfNo sabes qu\u00e9 compuestos se adaptan a tu investigaci\u00f3n? <a style=\"color: #0c2b3a;font-weight: bold;text-decoration: none\" href=\"https:\/\/portaltowellness.net\/research\/\">Explora el Centro de Investigaci\u00f3n \u2192<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>Inhibidor de miostatina (GDF-8). Se une y neutraliza la miostatina, el principal regulador negativo de la masa muscular esquel\u00e9tica. Estudiado en investigaci\u00f3n sobre masa muscular y composici\u00f3n corporal. Solo para uso en investigaci\u00f3n.<\/p>","protected":false},"featured_media":1090,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[35],"product_cat":[550,520,521,519],"product_tag":[429,438,430],"class_list":["post-698","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-hormone-circadian","product_cat-metabolic-research","product_cat-mitochondrial-longevity","product_cat-recovery-repair","product_tag-injectable","product_tag-myostatin","product_tag-research","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/698","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=698"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/1090"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=698"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=698"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=698"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=698"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}