{"id":699,"date":"2026-04-26T08:25:56","date_gmt":"2026-04-26T13:25:56","guid":{"rendered":"https:\/\/portaltowellness.net\/shop\/igf-1-lr3\/"},"modified":"2026-10-09T09:28:40","modified_gmt":"2026-10-09T14:28:40","slug":"igf-1-lr3","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/igf-1-lr3\/","title":{"rendered":"IGF-1 LR3 \u2013 1mg\/vial (Solo para Uso en Investigaci\u00f3n)"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><p><!-- wp:html --><\/p>\n<p><style>.ptw-product-research-link{background:#f6f3ec;border:1px solid #e0d9c8;border-left:4px solid #8a7a4d;border-radius:8px;padding:14px 18px;margin:16px 0 20px;font-size:15px;}.ptw-product-research-link__label{display:block;font-size:11px;font-weight:700;letter-spacing:.08em;text-transform:uppercase;color:#8a7a4d;margin-bottom:6px;}.ptw-product-research-link__link{display:block;color:#1a2b4c;font-weight:600;text-decoration:underline;margin-top:3px;}<\/style>\n<\/p>\n<p><!-- \/wp:html --><br \/><!-- wp:html --><\/p>\n<div class=\"ptw-product-research-link\"><span class=\"ptw-product-research-link__label\">Respaldado por la investigaci\u00f3n<\/span><a class=\"ptw-product-research-link__link\" href=\"https:\/\/portaltowellness.net\/research\/glp1-adjunct-peptide-research-guide\/\">Leer: Compuestos incret\u00ednicos y del eje de la hormona de crecimiento en la literatura \u2192<\/a><\/div>\n<p><!-- \/wp:html --><\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Descripci\u00f3n general<\/h3>\n<p>IGF-1 LR3 (Long-Arginine-3 IGF-1) es un an\u00e1logo sint\u00e9tico de acci\u00f3n prolongada del factor de crecimiento similar a la insulina 1 humano (IGF-1), dise\u00f1ado para aplicaciones de investigaci\u00f3n que requieren una activaci\u00f3n receptorial extendida y una menor uni\u00f3n a las IGFBP. Al sustituir el glutamato en la posici\u00f3n 3 por arginina y agregar una extensi\u00f3n pept\u00eddica de 13 amino\u00e1cidos en el extremo N-terminal, IGF-1 LR3 logra una uni\u00f3n notablemente reducida a las prote\u00ednas de uni\u00f3n al IGF (IGFBPs) y una vida media plasm\u00e1tica prolongada en comparaci\u00f3n con el IGF-1 nativo, lo que lo convierte en la herramienta de investigaci\u00f3n preferida para estudios sostenidos de la v\u00eda del receptor de IGF-1.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Qu\u00e9 es<\/h3>\n<p>IGF-1 LR3 es un an\u00e1logo sint\u00e9tico de 83 amino\u00e1cidos del IGF-1 humano, que incorpora una extensi\u00f3n N-terminal de 13 residuos y una sustituci\u00f3n Glu\u00b3\u2192Arg. Su peso molecular es de aproximadamente 9,117 Da. Presenta ~2\u20133% de la afinidad de uni\u00f3n a IGFBP del IGF-1 nativo, lo que resulta en una vida media estimada de 20\u201330 horas in vivo, frente a la vida media de ~12 minutos del IGF-1 nativo. N\u00famero CAS: 946870-92-4.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Principales aplicaciones de investigaci\u00f3n<\/h3>\n<ul>\n<li>Activaci\u00f3n del receptor de IGF-1 (IGF-1R) e investigaci\u00f3n de la se\u00f1alizaci\u00f3n posterior PI3K\/Akt\/mTOR<\/li>\n<li>Estudios de proliferaci\u00f3n, diferenciaci\u00f3n de mioblastos y cultivo de tejido muscular esquel\u00e9tico<\/li>\n<li>Investigaci\u00f3n de la activaci\u00f3n de c\u00e9lulas sat\u00e9lite y las v\u00edas de regeneraci\u00f3n muscular<\/li>\n<li>Investigaci\u00f3n de la se\u00f1alizaci\u00f3n anab\u00f3lica \u00f3sea, la funci\u00f3n de los osteoblastos y el crecimiento esquel\u00e9tico<\/li>\n<li>Estudios de farmacocin\u00e9tica de an\u00e1logos de IGF-1 de acci\u00f3n prolongada e interacciones con IGFBP<\/li>\n<li>Estudios de disociaci\u00f3n del eje GH\/IGF-1 \u2014 investigaci\u00f3n de la activaci\u00f3n del IGF-1R independiente de GH<\/li>\n<li>Neuroprotecci\u00f3n, supervivencia neuronal y biolog\u00eda del receptor de IGF-1 en el SNC<\/li>\n<li>Farmacolog\u00eda comparativa frente al IGF-1 nativo y fragmentos des(1-3) IGF-1<\/li>\n<\/ul>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Especificaciones t\u00e9cnicas<\/h3>\n<table style=\"width: 100%;border-collapse: collapse;margin: 10px 0\">\n<tbody>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Amino\u00e1cidos<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">83<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Peso molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~9,117 Da<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">N\u00famero CAS<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">946870-92-4<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Mecanismo<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Agonista del receptor de IGF-1 (vida media extendida)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Uni\u00f3n a IGFBP<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~2\u20133% respecto al IGF-1 nativo<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Pureza<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Forma<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Polvo liofilizado<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Tama\u00f1o del vial<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">1mg<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Almacenamiento<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u22124 \u00b0F a largo plazo<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"background: #fff8e7;border-top: 2px solid #d4a017;border-bottom: 2px solid #d4a017;padding: 10px;margin-top: 20px\"><strong>SOLO PARA USO EN INVESTIGACI\u00d3N.<\/strong> No est\u00e1 destinado al consumo humano ni veterinario, ni al diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ning\u00fan organismo regulador. Debe ser manipulado por personal de investigaci\u00f3n calificado en un entorno de laboratorio que cumpla con la normativa aplicable. Estas declaraciones no han sido evaluadas por la Administraci\u00f3n de Alimentos y Medicamentos (FDA).<\/p>\n<p style=\"margin-top: 20px;padding: 14px 18px;background: #f0f6fa;border-left: 4px solid #c9a44d;border-radius: 0 4px 4px 0;font-size: 0.9rem;line-height: 1.5\">\u00bfNo sabes qu\u00e9 compuestos se adaptan a tu investigaci\u00f3n? <a style=\"color: #0c2b3a;font-weight: bold;text-decoration: none\" href=\"https:\/\/portaltowellness.net\/research\/\">Explora el Centro de Investigaci\u00f3n \u2192<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>An\u00e1logo de IGF-1 de acci\u00f3n prolongada estudiado en investigaci\u00f3n de s\u00edntesis de prote\u00ednas y composici\u00f3n corporal. Solo para uso en investigaci\u00f3n.<\/p>","protected":false},"featured_media":1089,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[35],"product_cat":[550,520,521,519],"product_tag":[439,429,430],"class_list":["post-699","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-hormone-circadian","product_cat-metabolic-research","product_cat-mitochondrial-longevity","product_cat-recovery-repair","product_tag-igf","product_tag-injectable","product_tag-research","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/699","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=699"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/1089"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=699"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=699"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=699"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=699"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}