{"id":700,"date":"2026-04-26T07:25:59","date_gmt":"2026-04-26T13:25:59","guid":{"rendered":"https:\/\/portaltowellness.net\/shop\/methylene-blue\/"},"modified":"2026-09-15T06:49:58","modified_gmt":"2026-09-15T11:49:58","slug":"methylene-blue","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/methylene-blue\/","title":{"rendered":"Azul de Metileno \u2013 20mg \u00d7 100 tabletas (Solo para Uso en Investigaci\u00f3n)"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><h3 style=\"color: #1a7a6e;margin-top: 20px\">Descripci\u00f3n general<\/h3>\nEl azul de metileno (cloruro de metiltioninio) es el compuesto farmac\u00e9utico sint\u00e9tico m\u00e1s antiguo en uso cl\u00ednico y una de las mol\u00e9culas peque\u00f1as redox-activas m\u00e1s estudiadas en la investigaci\u00f3n biom\u00e9dica. Como agente de ciclado redox que funciona como transportador de electrones entre el NADH y el citocromo c en la cadena de transporte de electrones mitocondrial, el azul de metileno ha generado un intenso inter\u00e9s investigativo en farmacolog\u00eda mitocondrial, neuroprotecci\u00f3n y biolog\u00eda metab\u00f3lica. Su capacidad para aceptar y donar electrones en m\u00faltiples estados de oxidaci\u00f3n \u2014y de acceder al sistema nervioso central\u2014 lo ha convertido en una herramienta de investigaci\u00f3n excepcionalmente vers\u00e1til.\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">\u00bfQu\u00e9 es?<\/h3>\nEl azul de metileno tiene la f\u00f3rmula molecular C\u2081\u2086H\u2081\u2088ClN\u2083S, PM ~319.85 Da, n\u00famero CAS 61-73-4. Existe en dos estados redox interconvertibles: azul de metileno oxidado (azul) y leucoazul de metileno reducido (incoloro). En sistemas celulares, el azul de metileno evita la disfunci\u00f3n del Complejo I al transportar electrones del NADH directamente a la citocromo c oxidasa (Complejo IV). Atraviesa f\u00e1cilmente la barrera hematoencef\u00e1lica y se acumula en las mitocondrias.\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Principales aplicaciones de investigaci\u00f3n<\/h3>\n<ul>\n \t<li>Investigaci\u00f3n sobre el bypass de la cadena de transporte de electrones mitocondrial y la disfunci\u00f3n del Complejo I<\/li>\n \t<li>Estudios de respiraci\u00f3n celular, consumo de ox\u00edgeno y producci\u00f3n de ATP<\/li>\n \t<li>Investigaci\u00f3n sobre neuroprotecci\u00f3n e inhibici\u00f3n de la agregaci\u00f3n de prote\u00edna tau en modelos de neurodegeneraci\u00f3n<\/li>\n \t<li>Estudios sobre la eliminaci\u00f3n de especies reactivas de ox\u00edgeno (ROS) y mecanismos de defensa antioxidante<\/li>\n \t<li>Modelado precl\u00ednico de la enfermedad de Alzheimer \u2014 investigaci\u00f3n de las v\u00edas amiloide y tau<\/li>\n \t<li>Investigaci\u00f3n sobre flujo sangu\u00edneo cerebral, metabolismo de glucosa y neuroenerg\u00e9tica<\/li>\n \t<li>Farmacolog\u00eda de la inhibici\u00f3n de la monoaminooxidasa (MAO) y estudios del sistema dopamin\u00e9rgico<\/li>\n \t<li>Mecanismo de reversi\u00f3n de la metahemoglobinemia \u2014 investigaci\u00f3n de la interacci\u00f3n entre \u00f3xido n\u00edtrico y hemoglobina<\/li>\n<\/ul>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Especificaciones t\u00e9cnicas<\/h3>\n<table style=\"width: 100%;border-collapse: collapse;margin: 10px 0\">\n<tbody>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Compuesto<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Azul de Metileno (Cloruro de Metiltioninio)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">F\u00f3rmula molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">C\u2081\u2086H\u2081\u2088ClN\u2083S<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Peso molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~319.85 Da<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">N\u00famero CAS<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">61-73-4<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Mecanismo<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Agente de ciclado redox mitocondrial \/ Transportador de electrones de la CTE<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Pureza<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Forma<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Tableta oral (20mg)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Cantidad<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">100 tabletas por frasco<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Almacenamiento<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Temperatura ambiente, proteger de la luz<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"background: #fff8e7;border-top: 2px solid #d4a017;border-bottom: 2px solid #d4a017;padding: 10px;margin-top: 20px\"><strong>SOLO PARA USO EN INVESTIGACI\u00d3N.<\/strong> No est\u00e1 destinado al consumo humano ni veterinario, ni al diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ning\u00fan organismo regulador. Debe ser manejado por personal de investigaci\u00f3n calificado en un entorno de laboratorio que cumpla con la normativa aplicable. Estas declaraciones no han sido evaluadas por la Administraci\u00f3n de Alimentos y Medicamentos de los Estados Unidos.<\/p>\n<p style=\"margin-top: 20px;padding: 14px 18px;background: #f0f6fa;border-left: 4px solid #c9a44d;border-radius: 0 4px 4px 0;font-size: 0.9rem;line-height: 1.5\">\u00bfNo sabes qu\u00e9 compuestos se adaptan mejor a tu investigaci\u00f3n? <a style=\"color: #0c2b3a;font-weight: bold;text-decoration: none\" href=\"https:\/\/portaltowellness.net\/research\/\">Explora el Hub de Investigaci\u00f3n \u2192<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>Un compuesto de fenotiazina estudiado por su interacci\u00f3n con la cadena de transporte de electrones mitocondrial y como agente de ciclo redox en investigaciones publicadas in vitro y en animales. Suministrado solo para investigaci\u00f3n de laboratorio e identificaci\u00f3n.<\/p>","protected":false},"featured_media":719,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[35],"product_cat":[507,521],"product_tag":[442,441,232,434,430],"class_list":["post-700","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-neuropeptides","product_cat-mitochondrial-longevity","product_tag-cognitive","product_tag-mitochondria","product_tag-nootropic","product_tag-oral","product_tag-research","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/700","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=700"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/719"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=700"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=700"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=700"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=700"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}