{"id":710,"date":"2026-04-26T08:26:23","date_gmt":"2026-04-26T13:26:23","guid":{"rendered":"https:\/\/portaltowellness.net\/shop\/tesofensine\/"},"modified":"2026-10-09T09:28:01","modified_gmt":"2026-10-09T14:28:01","slug":"tesofensine","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/tesofensine\/","title":{"rendered":"Tesofensina \u2013 500mcg \u00d7 100 tabletas (Solo para uso en investigaci\u00f3n)"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><p><!-- wp:html --><\/p>\n<p><style>.ptw-product-research-link{background:#f6f3ec;border:1px solid #e0d9c8;border-left:4px solid #8a7a4d;border-radius:8px;padding:14px 18px;margin:16px 0 20px;font-size:15px;}.ptw-product-research-link__label{display:block;font-size:11px;font-weight:700;letter-spacing:.08em;text-transform:uppercase;color:#8a7a4d;margin-bottom:6px;}.ptw-product-research-link__link{display:block;color:#1a2b4c;font-weight:600;text-decoration:underline;margin-top:3px;}<\/style>\n<\/p>\n<p><!-- \/wp:html --><br \/><!-- wp:html --><\/p>\n<div class=\"ptw-product-research-link\"><span class=\"ptw-product-research-link__label\">Respaldado por la investigaci\u00f3n<\/span><a class=\"ptw-product-research-link__link\" href=\"https:\/\/portaltowellness.net\/research\/glp1-adjunct-peptide-research-guide\/\">Leer: Compuestos incret\u00ednicos y del eje de la hormona de crecimiento en la literatura \u2192<\/a><\/div>\n<p><!-- \/wp:html --><\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Descripci\u00f3n general<\/h3>\n<p>La tesofensina es un inhibidor triple de la recaptaci\u00f3n de monoaminas desarrollado originalmente por NeuroSearch A\/S para uso de investigaci\u00f3n en enfermedades neurodegenerativas y posteriormente estudiado en el campo de la ciencia metab\u00f3lica. Al inhibir la recaptaci\u00f3n de las tres principales catecolaminas \u2014 dopamina, norepinefrina y serotonina \u2014 la tesofensina ha generado inter\u00e9s en la literatura cient\u00edfica en torno a los circuitos de recompensa, los mecanismos de regulaci\u00f3n del apetito y el modelado de la homeostasis energ\u00e9tica del sistema nervioso central.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Qu\u00e9 es<\/h3>\n<p>La tesofensina (NS2330) es un derivado de feniltropano con f\u00f3rmula molecular C\u2081\u2087H\u2082\u2084ClNO (como sal HCl), PM aproximado de 312.84 Da, n\u00famero CAS 195875-84-4. Inhibe el transportador de dopamina (DAT), el transportador de norepinefrina (NET) y el transportador de serotonina (SERT) con distintas afinidades, produciendo un perfil de amplificaci\u00f3n de se\u00f1al monoamin\u00e9rgica amplio, diferente al de los inhibidores de recaptaci\u00f3n de un solo objetivo.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Aplicaciones clave en investigaci\u00f3n<\/h3>\n<ul>\n<li>Estudios de farmacolog\u00eda de inhibici\u00f3n triple de recaptaci\u00f3n de monoaminas y selectividad de receptores<\/li>\n<li>Investigaci\u00f3n sobre modulaci\u00f3n de las v\u00edas dopamin\u00e9rgica, noradren\u00e9rgica y serotonin\u00e9rgica centrales<\/li>\n<li>Estudios de mecanismos reguladores del apetito y la homeostasis energ\u00e9tica en modelos animales<\/li>\n<li>Investigaci\u00f3n del circuito de recompensa y el sistema dopamin\u00e9rgico mesol\u00edmbico<\/li>\n<li>Farmacolog\u00eda comparativa frente a inhibidores de recaptaci\u00f3n de monoaminas simples y duales<\/li>\n<li>Investigaci\u00f3n de biomarcadores en enfermedades neurodegenerativas (modelos precl\u00ednicos de Parkinson y Alzheimer)<\/li>\n<li>Estudios de regulaci\u00f3n de la tasa metab\u00f3lica, la termog\u00e9nesis y la ingesta de alimentos<\/li>\n<li>Investigaci\u00f3n sobre ocupaci\u00f3n y cin\u00e9tica del transportador de monoaminas en el sistema nervioso central<\/li>\n<\/ul>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Especificaciones t\u00e9cnicas<\/h3>\n<table style=\"width: 100%;border-collapse: collapse;margin: 10px 0\">\n<tbody>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Compuesto<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Tesofensina (NS2330)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Peso molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~312.84 Da (base libre)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">N\u00famero CAS<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">195875-84-4<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Mecanismo<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Inhibidor triple de recaptaci\u00f3n DAT\/NET\/SERT<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Pureza<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Forma<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Tableta oral (500 mcg)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Cantidad<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">100 tabletas por frasco<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Almacenamiento<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Temperatura ambiente, lejos de la humedad y la luz<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"background: #fff8e7;border-top: 2px solid #d4a017;border-bottom: 2px solid #d4a017;padding: 10px;margin-top: 20px\"><strong>SOLO PARA USO EN INVESTIGACI\u00d3N.<\/strong> No est\u00e1 destinado al consumo humano ni veterinario, ni al diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ninguna agencia regulatoria. Debe ser manipulado por personal de investigaci\u00f3n calificado en un entorno de laboratorio que cumpla con la normativa vigente. Estas declaraciones no han sido evaluadas por la Administraci\u00f3n de Alimentos y Medicamentos de los Estados Unidos.<\/p>\n<p style=\"margin-top: 20px;padding: 14px 18px;background: #f0f6fa;border-left: 4px solid #c9a44d;border-radius: 0 4px 4px 0;font-size: 0.9rem;line-height: 1.5\">\u00bfNo sabes qu\u00e9 compuestos se adaptan a tu investigaci\u00f3n? <a style=\"color: #0c2b3a;font-weight: bold;text-decoration: none\" href=\"https:\/\/portaltowellness.net\/research\/\">Explora el Centro de Investigaci\u00f3n \u2192<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>Oral | 500mcg \u00d7 100 comprimidos \u2014 Inhibidor triple de recaptaci\u00f3n. Solo para uso en investigaci\u00f3n.<\/p>","protected":false},"featured_media":1083,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[35],"product_cat":[520],"product_tag":[459,434,430],"class_list":["post-710","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-metabolic-research","product_tag-dopamine","product_tag-oral","product_tag-research","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/710","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=710"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/1083"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=710"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=710"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=710"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=710"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}