{"id":89,"date":"2025-03-08T17:51:14","date_gmt":"2025-03-08T23:51:14","guid":{"rendered":"https:\/\/portaltowellness.net\/?post_type=product&#038;p=89"},"modified":"2026-10-09T09:18:58","modified_gmt":"2026-10-09T14:18:58","slug":"gaba","status":"publish","type":"product","link":"https:\/\/portaltowellness.net\/es\/shop\/gaba\/","title":{"rendered":"GABA \u2013 100mg\/vial (Solo para uso en investigaci\u00f3n)"},"content":{"rendered":"<div class=\"notranslate\" translate=\"no\" data-wg-notranslate data-no-translation=\"\"><h3 style=\"color: #1a7a6e;margin-top: 20px\">Descripci\u00f3n general<\/h3>\n<p>El GABA (\u00e1cido gamma-aminobut\u00edrico) es el principal neurotransmisor inhibitorio del sistema nervioso central (SNC) de los mam\u00edferos, y media aproximadamente el 30\u201340% de toda la transmisi\u00f3n sin\u00e1ptica del SNC a trav\u00e9s de los receptores ionotr\u00f3picos GABA-A y GABA-C, y del receptor metabotr\u00f3pico GABA-B. Como agonista end\u00f3geno del sistema receptor inhibitorio m\u00e1s relevante desde el punto de vista farmacol\u00f3gico en el cerebro \u2014diana de las benzodiacepinas, barbit\u00faricos, neuroesteroides y anest\u00e9sicos generales\u2014, el GABA es uno de los neurotransmisores m\u00e1s ampliamente investigados en farmacolog\u00eda. El inter\u00e9s cient\u00edfico se extiende tambi\u00e9n a los sistemas de receptores GABA perif\u00e9ricos, incluyendo la se\u00f1alizaci\u00f3n GABA en c\u00e9lulas beta pancre\u00e1ticas y la biolog\u00eda de los receptores GABA en c\u00e9lulas inmunitarias.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Qu\u00e9 es<\/h3>\n<p>El GABA (\u00e1cido 4-aminobutanoico) es un amino\u00e1cido no proteinog\u00e9nico con f\u00f3rmula molecular C\u2084H\u2089NO\u2082, peso molecular aproximado de 103.12 Da, n\u00famero CAS 56-12-2. Se sintetiza a partir de L-glutamato mediante la glutamato descarboxilasa (GAD) utilizando fosfato de piridoxal (vitamina B6) como cofactor, y se cataboliza a trav\u00e9s del shunt del GABA (GABA transaminasa \u2192 semialdeh\u00eddo succ\u00ednico \u2192 succinato que entra al ciclo de Krebs). La activaci\u00f3n del receptor GABA-A aumenta directamente la conductancia de Cl\u207b, hiperpolarizando la membrana neuronal. La activaci\u00f3n del receptor GABA-B (acoplado a Gi) reduce el AMPc y modula los canales de K\u207a y Ca\u00b2\u207a.<\/p>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Principales aplicaciones de investigaci\u00f3n<\/h3>\n<ul>\n<li>Farmacolog\u00eda del receptor GABA-A \u2014 regulaci\u00f3n del canal de cloruro, composici\u00f3n de subunidades e investigaci\u00f3n de moduladores alost\u00e9ricos<\/li>\n<li>Se\u00f1alizaci\u00f3n del receptor GABA-B (acoplado a Gi), inhibici\u00f3n presin\u00e1ptica y estudios de modulaci\u00f3n de canales de K\u207a\/Ca\u00b2\u207a<\/li>\n<li>Formaci\u00f3n de sinapsis GABA\u00e9rgicas, expresi\u00f3n del transportador de GABA (GAT1-4) y estudios de recaptaci\u00f3n<\/li>\n<li>Investigaci\u00f3n del equilibrio glutamato\/GABA y de la neurotransmisi\u00f3n excitatoria\/inhibitoria<\/li>\n<li>Estudios de se\u00f1alizaci\u00f3n GABA en c\u00e9lulas beta pancre\u00e1ticas y regulaci\u00f3n paracrina de la secreci\u00f3n de glucag\u00f3n<\/li>\n<li>Investigaci\u00f3n sobre la expresi\u00f3n de receptores GABA en c\u00e9lulas inmunitarias y su funci\u00f3n inmunomoduladora<\/li>\n<li>Estudios de mecanismos ansiol\u00edticos y sedantes \u2014 investigaci\u00f3n de selectividad de subunidades del receptor GABA-A<\/li>\n<li>Estudios del metabolismo del shunt del GABA, integraci\u00f3n en el ciclo de Krebs y neuroenerg\u00e9tica<\/li>\n<\/ul>\n<h3 style=\"color: #1a7a6e;margin-top: 20px\">Especificaciones t\u00e9cnicas<\/h3>\n<table style=\"width: 100%;border-collapse: collapse;margin: 10px 0\">\n<tbody>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Compuesto<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u00c1cido \u03b3-aminobut\u00edrico (GABA)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">F\u00f3rmula molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">C\u2084H\u2089NO\u2082<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Peso molecular<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">~103.12 Da<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">N\u00famero CAS<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">56-12-2<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Mecanismo<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Agonista end\u00f3geno de los receptores GABA-A (ionotr\u00f3pico) y GABA-B (metabotr\u00f3pico)<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Pureza<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">\u226598% (especificaci\u00f3n del proveedor)<\/td>\n<\/tr>\n<tr style=\"background: #eaf5f3\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Forma<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Polvo liofilizado<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Tama\u00f1o del vial<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">100mg<\/td>\n<\/tr>\n<tr style=\"background: #fff\">\n<td style=\"padding: 6px 10px;font-weight: bold;width: 35%;border: 1px solid #ccc\">Almacenamiento<\/td>\n<td style=\"padding: 6px 10px;border: 1px solid #ccc\">Temperatura ambiente; sellado, alejado de la humedad<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"background: #fff8e7;border-top: 2px solid #d4a017;border-bottom: 2px solid #d4a017;padding: 10px;margin-top: 20px\"><strong>SOLO PARA USO EN INVESTIGACI\u00d3N.<\/strong> No est\u00e1 destinado al consumo humano ni veterinario, ni al diagn\u00f3stico m\u00e9dico, tratamiento o prevenci\u00f3n de ninguna enfermedad o condici\u00f3n. Este producto no ha sido evaluado por la FDA ni por ning\u00fan organismo regulador. Debe ser manipulado por personal de investigaci\u00f3n calificado en un entorno de laboratorio adecuado. Estas declaraciones no han sido evaluadas por la Administraci\u00f3n de Alimentos y Medicamentos de los Estados Unidos.<\/p>\n<p style=\"margin-top: 20px;padding: 14px 18px;background: #f0f6fa;border-left: 4px solid #c9a44d;border-radius: 0 4px 4px 0;font-size: 0.9rem;line-height: 1.5\">\u00bfNo sabes qu\u00e9 compuestos se adaptan mejor a tu investigaci\u00f3n? <a style=\"color: #0c2b3a;font-weight: bold;text-decoration: none\" href=\"https:\/\/portaltowellness.net\/research\/\">Explora el Hub de Investigaci\u00f3n \u2192<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"<p>El \u00e1cido gamma-aminobut\u00edrico (GABA), el principal neurotransmisor inhibidor, estudiado en la farmacolog\u00eda de los receptores GABA. Suministrado \u00fanicamente para investigaci\u00f3n en laboratorio e identificaci\u00f3n.<\/p>","protected":false},"featured_media":1118,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ptw_protocol_fit":"","ptw_why_this":"","ptw_coa_url":"","ptw_science_overview":"","ptw_science_research":"","ptw_science_stack":"","_ptw_batch_number":""},"product_brand":[35],"product_cat":[550,521],"product_tag":[429,92,95,430],"class_list":["post-89","product","type-product","status-publish","has-post-thumbnail","product_brand-portal-to-wellness","product_cat-hormone-circadian","product_cat-mitochondrial-longevity","product_tag-injectable","product_tag-neurotransmitter","product_tag-relaxation","product_tag-research","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","sale","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product\/89","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/comments?post=89"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media\/1118"}],"wp:attachment":[{"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/media?parent=89"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_brand?post=89"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_cat?post=89"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/portaltowellness.net\/es\/wp-json\/wp\/v2\/product_tag?post=89"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}