# Incretin Agonists — GLP-1 and Amylin Research Compounds

These compounds act on the incretin and amylin receptor systems. They are grouped below by receptor coverage — which receptors each one binds — not by any order of use. Portal to Wellness does not publish protocols, combinations or quantities.

---

## GIP and GLP-1 dual agonists

Tirzepatide binds both the GIP and the GLP-1 receptor. Much of the published literature on dual incretin agonism is built on this compound.

- [[Image: Tirzepatide – 60mg/vial (Research Use Only)]](https://portaltowellness.net/shop/tirzepatide-60mg/) [Subscribe & save 10%](https://portaltowellness.net/shop/tirzepatide-60mg/) Sale! [Add to cart](https://portaltowellness.net/shop/tirzepatide-60mg/?add-to-cart=385)

Best Sellers
[## Tirzepatide – 60mg/vial (Research Use Only)](https://portaltowellness.net/shop/tirzepatide-60mg/)

Rated **5.00** out of 5

Original price was: $116.47.Current price is: $99.00. — or subscribe to save 10%
[Add to cart](https://portaltowellness.net/shop/tirzepatide-60mg/?add-to-cart=385)

### GLP-1 receptor agonists

Semaglutide binds the GLP-1 receptor alone, and is the reference compound for single-receptor incretin agonism in the published literature. It is supplied in two vial sizes; vial size is a quantity of material, not a stage in a research programme.

- [Lowest cost per mg [Image: Semaglutide – 30mg/vial — Research Use Only]](https://portaltowellness.net/shop/semaglutide/) [Subscribe & save 10%](https://portaltowellness.net/shop/semaglutide/) Sale! [Add to cart](https://portaltowellness.net/shop/semaglutide/?add-to-cart=470)

Best Sellers
[## Semaglutide – 30mg/vial — Research Use Only](https://portaltowellness.net/shop/semaglutide/)
Original price was: $81.18.Current price is: $69.00. — or subscribe to save 10%
[Add to cart](https://portaltowellness.net/shop/semaglutide/?add-to-cart=470)
- [Smallest size [Image: Semaglutide – 5mg/vial — Research Use Only]](https://portaltowellness.net/shop/semaglutide-5mg-vial-research-use-only/) [Subscribe & save 10%](https://portaltowellness.net/shop/semaglutide-5mg-vial-research-use-only/) Sale! [Add to cart](https://portaltowellness.net/shop/semaglutide-5mg-vial-research-use-only/?add-to-cart=1148)

Best Sellers
[## Semaglutide – 5mg/vial — Research Use Only](https://portaltowellness.net/shop/semaglutide-5mg-vial-research-use-only/)
Original price was: $28.24.Current price is: $24.00. — or subscribe to save 10%
[Add to cart](https://portaltowellness.net/shop/semaglutide-5mg-vial-research-use-only/?add-to-cart=1148)

---

## Triple receptor agonists

---

## Additional compounds in this class

Cagrilintide, supplied on its own as an amylin analogue, and 5-Amino-1MQ, which inhibits nicotinamide N-methyltransferase (NNMT) and is not an incretin agonist.

- [[Image: 5-Amino-1MQ – 50mg/vial (Research Use Only)]](https://portaltowellness.net/shop/5-amino-1mq/) Sale! [Add to cart](https://portaltowellness.net/shop/5-amino-1mq/?add-to-cart=134)

Metabolic Research
[## 5-Amino-1MQ – 50mg/vial (Research Use Only)](https://portaltowellness.net/shop/5-amino-1mq/)
Original price was: $84.71.Current price is: $72.00.
[Add to cart](https://portaltowellness.net/shop/5-amino-1mq/?add-to-cart=134)
- [[Image: Cagrilintide – 10mg/vial (Research Use Only)]](https://portaltowellness.net/shop/cagrilintide/) [Subscribe & save 10%](https://portaltowellness.net/shop/cagrilintide/) Sale! [Add to cart](https://portaltowellness.net/shop/cagrilintide/?add-to-cart=696)

Metabolic Research
[## Cagrilintide – 10mg/vial (Research Use Only)](https://portaltowellness.net/shop/cagrilintide/)
Original price was: $111.76.Current price is: $95.00. — or subscribe to save 10%
[Add to cart](https://portaltowellness.net/shop/cagrilintide/?add-to-cart=696)

---

*The [Metabolic Research Kit](https://portaltowellness.net/metabolic-research-kit/) page carries compound-level write-ups and mechanism detail for this class.*

---

## 📚 From the Research Library: GLP-1 and metabolic research

Go deeper with our Research Library — published literature summaries behind these compounds.

- [SURMOUNT-MMO Trial Explained](https://portaltowellness.net/research/surmount-mmo-trial-tirzepatide-mortality/)
- [Stopping a GLP-1: What the Research Shows About Regain](https://portaltowellness.net/research/stopping-a-glp-1-weaning-off-weight-regain/)
- [Injectable vs. Oral GLP-1: What Researchers Need to Know](https://portaltowellness.net/research/injectable-vs-oral-glp1-what-researchers-need-to-know/)

### Backed by the Research

Research on These Compounds [Tirzepatide: Mechanism & Research Guide](https://portaltowellness.net/research/tirzepatide-research-guide/) [Semaglutide: Mechanism & Research Guide](https://portaltowellness.net/research/semaglutide-research-guide/) [Cagrilintide + Semaglutide: REDEFINE-1 Trial Data](https://portaltowellness.net/research/cagrilintide-semaglutide-redefine-1-trial-data/)

More Research [Browse the full PTW Research Hub →](https://portaltowellness.net/research/)

---

Source: https://portaltowellness.net/incretin-agonists/
Research use only. Terms: https://portaltowellness.net/research-use-only/