# Neuropeptide Research Compounds

COGNITIVE PERFORMANCE — RESEARCH COMPOUNDS

# Three compounds, three different questions in cognitive research.

Semax, Selank and P21 — each studied for a different aspect of neuroplasticity and stress signalling. Available individually, or together in one order.

[Bundle & Save 10% →](https://portaltowellness.net/shop/cognitive-performance-stack/)
[View Individual Compounds](https://portaltowellness.net/shop/cognitive-performance-stack/)

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📚 Published research linked per compound

Why This Stack

## What these compounds are studied for.

Semax is a fragment of ACTH studied for effects on BDNF expression and attention in animal models. Selank is derived from tuftsin and studied for anxiolytic activity without the sedation associated with benzodiazepines. P21 is derived from CNTF and studied for whether it crosses the blood-brain barrier and influences BDNF at the transcriptional level. Those are three separate research questions with three separate evidence bases. Grouping them here is a purchasing convenience. It is not a claim that they act together, and no combination of them has been shown to be safe or effective for any use in people.

Compound Composition

## What’s in this stack.

COMPOUND 01

Semax — 10mg/vial

Synthetic analogue of ACTH(4-7). Studied in animal models for effects on BDNF expression and on dopamine and serotonin turnover in limbic regions.

Retail: $30.00

$27.00 with bundle

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COMPOUND 02

Selank — 10mg/vial

Heptapeptide analogue of tuftsin. Studied for anxiolytic activity in animal models without the sedation associated with benzodiazepines; also studied for effects on enkephalin metabolism.

Retail: $29.00

$26.10 with bundle

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COMPOUND 03

P21 (P021) — 5mg × 10 vials

CNTF-derived peptide. Studied for whether it crosses the blood-brain barrier and for effects on BDNF at the transcriptional level in research models.

Retail: $299.00

$269.10 with bundle

Mechanisms

## What the published work describes.

1

#### Semax — BDNF Pathway Activation

A synthetic analogue of ACTH(4-7), Semax increases BDNF (Brain-Derived Neurotrophic Factor) expression, enhances dopaminergic and serotonergic turnover in the frontal cortex and limbic system, and supports working memory consolidation in research models.

2

#### Selank — Stress-Resilient Cognition

A heptapeptide analogue of tuftsin (Thr-Lys-Pro-Arg-Pro-Gly-Pro). Research reports effects on enkephalin catabolism and GABA-A receptor expression, and anxiolytic activity without sedation in animal models. Whether any of that translates to a person is not established.

3

#### P21 — Gene-Level Neuroplasticity

Derived from CNTF (Ciliary Neurotrophic Factor), P21 is designed to cross the blood-brain barrier and upregulate BDNF at the transcription level. Research models show improvements in neurogenesis, dendritic spine density, and cognitive function — including in aging subjects.

**Research Note:** Portal to Wellness does not publish administration guidance. We do not provide dosing, routes, schedules, cycling or combination advice, and we cannot answer questions about use in humans or animals. Published trial and preclinical literature is where pharmacokinetic and administration data belongs; the compound pages below link the primary sources.

Bundle Pricing

## Save 10% when you buy these together.

Cognitive Performance Kit — all three compounds

Semax — 10mg/vial
$27.00

Selank — 10mg/vial
$26.10

P21 (P021) — 5mg × 10 vials
$269.10

Bundle Total
$322.20

You save $35.80 vs. buying them separately ($358.00)

[Cognitive Performance Kit — all three compounds →](https://portaltowellness.net/shop/cognitive-performance-stack/)

Bundle pricing applied automatically at checkout. Each compound is also available individually.

All products on Portal to Wellness are sold for research purposes only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm that you are a qualified researcher.

### Backed by the Research

Research on These Compounds [Semax, Selank & Pinealon: What the Research Shows About Nootropic Peptides](https://portaltowellness.net/research/semax-selank-pinealon-what-the-research-shows-about-nootropic-peptides/) [Longevity Research 101: Compound Classes by Biological System](https://portaltowellness.net/research/longevity-research-101-compound-classes-by-biological-system/)

Shop the Compounds [Semax – 10mg/vial](https://portaltowellness.net/shop/semax-10mg-vial/) [Selank – 10mg/vial](https://portaltowellness.net/shop/selank-10mg-vial/) [P21 (P021) – 5mg × 10 vials](https://portaltowellness.net/shop/p21-p021-5-mg-10-vials-research-use-only/)

More Research [Browse the full PTW Research Hub →](https://portaltowellness.net/research/)

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Source: https://portaltowellness.net/neuropeptide-cognitive-kit/
Research use only. Terms: https://portaltowellness.net/research-use-only/