# PTW Research Hub The home base for everything Portal to Wellness publishes on peptide and wellness-compound research — featured studies, FDA and regulatory tracking, and every topic area in one place. All content is for research purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Search the Research Hub Try a compound name (e.g. “BPC-157”), a product, a research guide, or a research topic. 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[Read the Article](https://portaltowellness.net/research/fda-warning-letters-glp1-telehealth-crackdown/) ## Latest Research - [Wegovy Pill Total Monthly Cost, Explained](https://portaltowellness.net/research/wegovy-pill-total-monthly-cost/) - [Biomarkers vs Clinical Outcomes in Research](https://portaltowellness.net/research/biomarkers-vs-clinical-outcomes-research/) - [Compounded Peptide vs Research Peptide](https://portaltowellness.net/research/compounded-peptide-vs-research-peptide/) - [GLP-1 Prior Authorization Data](https://portaltowellness.net/research/glp-1-prior-authorization-data/) - [GLP-1 vs. Bariatric Surgery in Teens: What New Data Shows](https://portaltowellness.net/research/glp-1-bariatric-surgery-teens/) - [GLP-1s and Eating Disorder Risk](https://portaltowellness.net/research/glp-1-eating-disorder-risk/) ## FDA & Regulatory Updates Tracking the policy and regulatory landscape around peptide and GLP-1 research — for informational purposes only, not legal or medical advice. - [What Determines Regulatory Status](https://portaltowellness.net/research/what-determines-regulatory-status/) - [What the FDA’s July Peptide Meeting Actually Means: 5 Things Every Researcher Should Understand](https://portaltowellness.net/research/fda-peptide-meeting-what-it-actually-means/) - [FDA Is Reviewing Popular Peptides: What Researchers Should Know Before the July 23–24 Advisory Meeting](https://portaltowellness.net/research/fda-peptide-review-july-2026/) - [Medicare Is Covering GLP-1s for Weight Loss: What This Means for the Future of Obesity Care](https://portaltowellness.net/research/medicare-glp1-coverage-2026/) ## Most Read Editorially curated for now — we’ll switch this to real traffic data once analytics reporting is connected. - [NAD+ Explained: What It Is, Why Levels Decline, and What the Science Actually Says](https://portaltowellness.net/research/what-is-nad-plus/) - [Recovery & Repair Research Compounds: A Complete Guide](https://portaltowellness.net/research/recovery-repair-research-compounds-guide/) - [BPC-157: What the Preclinical Research Actually Shows](https://portaltowellness.net/research/bpc-157-preclinical-research/) - [Semax, Selank & Pinealon: What the Research Shows About Nootropic Peptides](https://portaltowellness.net/research/semax-selank-pinealon-what-the-research-shows-about-nootropic-peptides/) - [Thymosin Alpha-1 & LL-37: What the Research Says About Immune-Modulating Peptides](https://portaltowellness.net/research/thymosin-alpha-1-ll-37-what-the-research-says-about-immune-modulating-peptides/) - [DSIP & Epithalon: What the Research Says About Sleep and Circadian Peptides](https://portaltowellness.net/research/dsip-epithalon-what-the-research-says-about-sleep-and-circadian-peptides/) ## Browse by Topic ### Metabolic & GLP-1 - [Weight Loss vs. Body Composition: Why Muscle Matters During GLP-1 Research](https://portaltowellness.net/research/weight-loss-vs-body-composition-glp1-muscle/) - [5 Questions Smart Researchers Should Ask Before Buying Peptides](https://portaltowellness.net/research/5-questions-before-buying-peptides/) [Browse: Metabolic & GLP-1 →](https://portaltowellness.net/metabolic-research-kit/) ### Recovery & Repair - [TB-500 (Thymosin Beta-4): What the Research Explores](https://portaltowellness.net/research/tb-500-thymosin-beta-4-research/) - [GHK-Cu: Copper Tripeptide Research Overview](https://portaltowellness.net/research/ghk-cu-copper-peptide-research/) - [BPC-157 and TB-500: Preclinical Literature Compared](https://portaltowellness.net/research/the-recovery-stack-how-bpc-157-and-tb-500-work-together/) [Browse: Recovery & Repair →](https://portaltowellness.net/tissue-repair-kit/) [BPC-157: formats, specifications and pricing →](https://portaltowellness.net/bpc-157/) ### Energy & Longevity - [Why Researchers Study NAD+: Energy, Longevity & the Hallmarks of Aging](https://portaltowellness.net/research/nad-plus-benefits-research/) - [NMN vs. NR: How These Two NAD+ Precursors Compare](https://portaltowellness.net/research/nmn-vs-nr/) - [MOTS-c: The Mitochondrial-Derived Peptide Explained](https://portaltowellness.net/research/mots-c-mitochondrial-peptide-research/) [Browse: Energy & Longevity →](https://portaltowellness.net/longevity-essentials-kit/) ### Sleep & Regeneration - [DSIP & Epithalon: What the Research Says About Sleep and Circadian Peptides](https://portaltowellness.net/research/dsip-epithalon-what-the-research-says-about-sleep-and-circadian-peptides/) [Growth-Hormone Axis & Circadian Signalling Research →](https://portaltowellness.net/circadian-regulation-kit/) ### Cognitive - [Semax, Selank & Pinealon: What the Research Shows About Nootropic Peptides](https://portaltowellness.net/research/semax-selank-pinealon-what-the-research-shows-about-nootropic-peptides/) [Neuropeptide Research Compounds →](https://portaltowellness.net/neuropeptide-cognitive-kit/) ### Immune & Protective - [Thymosin Alpha-1 & LL-37: What the Research Says About Immune-Modulating Peptides](https://portaltowellness.net/research/thymosin-alpha-1-ll-37-what-the-research-says-about-immune-modulating-peptides/) [Browse: Immune & Protective →](https://portaltowellness.net/immune-modulators/) ## Research Guides Structured research guides organized by goal, built from the Research Library’s compound-level findings. - [Incretin and Amylin Receptor Research Guide](https://portaltowellness.net/metabolic-research-kit/) - [Repair-Pathway Research Compounds](https://portaltowellness.net/tissue-repair-kit/) - [Neuropeptide Research Compounds](https://portaltowellness.net/neuropeptide-cognitive-kit/) - [Growth-Hormone Axis & Circadian Signalling Research](https://portaltowellness.net/circadian-regulation-kit/) - [Longevity Essentials Research Guide](https://portaltowellness.net/longevity-essentials-kit/) - [Incretin & Amylin Receptor Research Compounds](https://portaltowellness.net/metabolic-optimization-kit/) - [Research Compound Index](https://portaltowellness.net/research-compound-index/) - [Ageing-Biology Research Index](https://portaltowellness.net/longevity-compound-index/) - [Getting Started: Longevity Research 101](https://portaltowellness.net/research/longevity-research-101-compound-classes-by-biological-system/) ## Video Library *Coming soon.* We’re building out video breakdowns of key research to pair with the written Research Library — check back soon. ## Get New Research First Subscribe for new Research Library articles, FDA/regulatory updates, and research digests as they publish. [Subscribe →](https://manage.kmail-lists.com/subscriptions/subscribe?a=S5zDaE&g=WwiyCr) ## Complete index Every research article and guide we have published, newest first. Research Library # The Science Behind the Compounds Literature summaries organised by compound and mechanism. ◎ Compound Deep Dives 8 min read ## [GHK-Cu: Fibroblast Gene Expression Studies](https://portaltowellness.net/research/peptides-collagen-production-research/) GHK-Cu is the most studied peptide for collagen synthesis research — not a collagen protein itself, but a signaling peptide shown to upregulate collagen I/III gene expression in fibroblast studies. [Read Guide](https://portaltowellness.net/research/peptides-collagen-production-research/) ◎ Compound Deep Dives 8 min read ## [Minoxidil and Dutasteride: Mechanism Overview](https://portaltowellness.net/research/hair-loss-research-minoxidil-dutasteride/) Evidence & Research Status Evidence LevelPreclinical / Early-Stage Research FDA StatusNot FDA-approved for human use Regulatory StatusResearch Use Only (RUO) […] [Read Guide](https://portaltowellness.net/research/hair-loss-research-minoxidil-dutasteride/) ◎ Compound Deep Dives 8 min read ## [Mitochondrial Peptide Comparison: SS-31, MOTS-c, and NAD+](https://portaltowellness.net/research/mitochondrial-peptide-comparison-ss31-mots-c-nad/) Evidence & Research Status Evidence LevelEmerging Human Research FDA StatusNot FDA-approved for human use Regulatory StatusResearch Use Only (RUO) — […] [Read Guide](https://portaltowellness.net/research/mitochondrial-peptide-comparison-ss31-mots-c-nad/) ◎ Research Briefs 8 min read Evidence & Research Status Evidence LevelExtensive Human Clinical Data FDA StatusNot FDA-approved for human use Regulatory StatusResearch Use Only (RUO) […] ◎ Compound Deep Dives 8 min read ## [Incretin and Growth-Hormone-Axis Compounds in the Literature](https://portaltowellness.net/research/glp1-adjunct-peptide-research-guide/) How GLP-1/GIP/amylin compounds relate to growth-hormone-axis, myostatin-pathway, and mitochondrial-support peptides in published research – including the BELIEVE trial data on muscle preservation. Research Use Only. [Read Guide](https://portaltowellness.net/research/glp1-adjunct-peptide-research-guide/) ◎ Research Briefs 8 min read ## [GLP-1 Additives: What a New JAMA Study Found](https://portaltowellness.net/research/glp-1-additives-compounding-study/) Evidence & Research Status Evidence LevelExtensive Human Clinical Data FDA StatusNot FDA-approved for human use Regulatory StatusResearch Use Only (RUO) […] [Read Guide](https://portaltowellness.net/research/glp-1-additives-compounding-study/) ◎ Research Briefs 8 min read ## [Obesity Subtype Predicts Tirzepatide Response](https://portaltowellness.net/research/obesity-subtype-tirzepatide-response/) Evidence & Research Status Evidence LevelExtensive Human Clinical Data FDA StatusNot FDA-approved for human use Regulatory StatusResearch Use Only (RUO) […] [Read Guide](https://portaltowellness.net/research/obesity-subtype-tirzepatide-response/) ◎ Compound Deep Dives 8 min read ## [Semaglutide: Mechanism, Clinical Trial Data & Research Guide](https://portaltowellness.net/research/semaglutide-research-guide/) Semaglutide is a GLP-1 receptor mono-agonist, FDA-approved as Ozempic, Wegovy, and Rybelsus for prescription human use. This research guide covers its mechanism, STEP/SELECT trial data including the SELECT cardiovascular outcomes trial, tolerability findings, and how it compares to tirzepatide and retatrutide. Research Use Only. [Read Guide](https://portaltowellness.net/research/semaglutide-research-guide/) ◎ Compound Deep Dives 8 min read ## [Tirzepatide: Mechanism, Clinical Trial Data & Research Guide](https://portaltowellness.net/research/tirzepatide-research-guide/) Tirzepatide is a dual GIP/GLP-1 receptor agonist, FDA-approved as Mounjaro and Zepbound for prescription human use. This research guide covers its mechanism, SURPASS/SURMOUNT trial data, tolerability findings including the ongoing SURMOUNT-MMO outcomes trial, and how it compares to semaglutide and retatrutide. Research Use Only. [Read Guide](https://portaltowellness.net/research/tirzepatide-research-guide/) ◎ Research Briefs 8 min read ## [Wegovy Pill Total Monthly Cost, Explained](https://portaltowellness.net/research/wegovy-pill-total-monthly-cost/) Evidence & Research Status Evidence LevelExtensive Human Clinical Data FDA StatusNot FDA-approved for human use Regulatory StatusResearch Use Only (RUO) […] [Read Guide](https://portaltowellness.net/research/wegovy-pill-total-monthly-cost/) ◎ Research Briefs 8 min read Evidence & Research Status Evidence LevelExtensive Human Clinical Data FDA StatusNot FDA-approved for human use Regulatory StatusResearch Use Only (RUO) […] ◎ Research Briefs 8 min read ## [Biomarkers vs Clinical Outcomes in Research](https://portaltowellness.net/research/biomarkers-vs-clinical-outcomes-research/) Evidence & Research Status Evidence LevelEmerging Human Research FDA StatusNot FDA-approved for human use Regulatory StatusResearch Use Only (RUO) — […] [Read Guide](https://portaltowellness.net/research/biomarkers-vs-clinical-outcomes-research/) ### Ready to Go Deeper? Every guide maps to a specific compound or stack available in the PTW catalog. Browse by research area and find what your research guide is missing. [Browse research compounds →](https://portaltowellness.net/shop/) filterBtns.forEach(function(btn) { btn.addEventListener('click', function() { filterBtns.forEach(function(b) { b.classList.remove('is-active'); }); btn.classList.add('is-active'); var filter = btn.getAttribute('data-filter'); cards.forEach(function(card) { if (filter === 'all') { card.style.display = ''; } else { var cats = card.getAttribute('data-categories') || ''; card.style.display = cats.indexOf(filter) !== -1 ? 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