# Pinealon – 20mg/vial (Research Use Only)

### Overview

Pinealon is a synthetic tripeptide bioregulator (Glu-Asp-Arg) developed at the St. Petersburg Institute of Bioregulation and Gerontology as part of the cytomedine research program — a class of short peptide bioregulators derived from tissue-specific polypeptides originally isolated from organ extracts. As a peptide bioregulator associated with pineal gland-derived research compounds, Pinealon has been studied in published literature examining neuronal gene expression, neuroprotective mechanisms, retinal cell biology, and circadian neuroendocrine research alongside the broader Khavinson peptide bioregulator series.

### What It Is

Pinealon is a synthetic Glu-Asp-Arg tripeptide with MW approximately 403 Da, CAS number 188922-50-1. Like other cytomedine peptide bioregulators (Epithalon, Thymalin, Cortexin series), Pinealon is believed to act via epigenetic mechanisms — interacting with DNA regulatory regions through electrostatic interactions with histones — rather than through conventional receptor binding. Published cell biology research has examined Pinealon’s effects on neuronal differentiation markers, DNA oxidative damage indicators, and protein expression profiles in neuronal and retinal cell preparations.

### Key Research Applications

- Cytomedine peptide bioregulator biology and epigenetic gene expression regulation research
- Neuroprotection and neuronal survival marker studies in oxidative stress models
- Retinal ganglion cell and photoreceptor biology research
- Circadian biology and pineal gland function studies
- DNA oxidative damage response and base excision repair pathway research
- Neuronal differentiation and neurite outgrowth marker studies in cell culture systems
- Comparative Khavinson peptide bioregulator research (Pinealon vs. Epithalon, Cortexin)
- Aging-associated neurological tissue biology and longevity marker studies

### Technical Specifications

| Amino Acids | 3 (Glu-Asp-Arg) |
| --- | --- |
| Molecular Weight | ~403 Da |
| CAS Number | 188922-50-1 |
| Classification | Cytomedine peptide bioregulator (pineal-derived) |
| Purity | ≥98% (supplier specification) |
| Form | Lyophilized powder |
| Vial Size | 20mg |
| Storage | −4 °F long-term |

**FOR RESEARCH USE ONLY.** Not intended for human or veterinary consumption, medical diagnosis, treatment, or prevention of any disease or condition. This product has not been evaluated by the FDA or any regulatory agency. Must be handled by qualified research personnel in a compliant laboratory setting. These statements have not been evaluated by the Food and Drug Administration.

Not sure which compounds fit your research? [Browse the Research Hub →](https://portaltowellness.net/research/)

### Related research (educational)

- [Semax, Selank & Pinealon: What the Research Shows About Nootropic Peptides](https://portaltowellness.net/research/semax-selank-pinealon-what-the-research-shows-about-nootropic-peptides/)
- [Overlapping Pathways in Circadian, Repair and Mitochondrial Biology](https://portaltowellness.net/research/sleep-repair-energy-one-system/)

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Research use only. Terms: https://portaltowellness.net/research-use-only/