# SLU-PP-332 – 100mg × 60 capsules (Research Use Only)

### Overview

SLU-PP-332 is a synthetic small-molecule agonist of the estrogen-related receptor alpha (ERRα) and related ERR isoforms (ERRβ, ERRγ), receptor subtypes that serve as master transcriptional regulators of mitochondrial biogenesis, oxidative phosphorylation gene networks, and skeletal muscle metabolic programming. As a research-characterized “exercise mimetic” compound, SLU-PP-332 has attracted significant investigative attention for its ability to activate genetic programs associated with aerobic endurance adaptation without physical exertion.

### What It Is

SLU-PP-332 is a synthetic ERRα/β/γ pan-agonist developed at St. Louis University, with molecular formula C₂₃H₂₀N₂O₃S, MW approximately 408.49 Da. It binds the ligand-binding domain of ERR receptors and activates downstream transcriptional programs including PGC-1α co-activation, OXPHOS gene upregulation, and fatty acid oxidation pathway enhancement. CAS number: 2750443-00-0.

### Key Research Applications

- ERRα/β/γ receptor binding, activation, and transcriptional coactivator recruitment studies
- Mitochondrial biogenesis gene network (PGC-1α pathway) activation research
- Oxidative phosphorylation complex expression and electron transport chain function studies
- Skeletal muscle fiber type transition and slow-twitch oxidative capacity research
- Exercise mimetic pharmacology and aerobic endurance biomarker studies in animal models
- Fatty acid oxidation, lipid catabolism, and metabolic substrate utilization research
- Heart failure, metabolic disease, and sarcopenia preclinical modeling
- Comparative ERR agonist pharmacology and isoform selectivity characterization

### Technical Specifications

| Compound | SLU-PP-332 |
| --- | --- |
| Molecular Formula | C₂₃H₂₀N₂O₃S |
| Molecular Weight | ~408.49 Da |
| CAS Number | 2750443-00-0 |
| Mechanism | ERRα/β/γ Pan-Agonist (Exercise Mimetic) |
| Purity | ≥98% (supplier specification) |
| Form | Oral capsule (100mg) |
| Quantity | 60 capsules per bottle |
| Storage | Cool, dry place away from heat, moisture and direct light |

**FOR RESEARCH USE ONLY.** Not intended for human or veterinary consumption, medical diagnosis, treatment, or prevention of any disease or condition. This product has not been evaluated by the FDA or any regulatory agency. Must be handled by qualified research personnel in a compliant laboratory setting. These statements have not been evaluated by the Food and Drug Administration.

Not sure which compounds fit your research? [Browse the Research Hub →](https://portaltowellness.net/research/)

---

Source: https://portaltowellness.net/shop/slu-pp-332/
Research use only. Terms: https://portaltowellness.net/research-use-only/