# Thymalin – 10mg/vial — Research Use Only

### Overview

Thymalin is a synthetic peptide bioregulator derived from calf thymus tissue extract (Thymalin polypeptide complex), developed as part of the St. Petersburg Institute of Bioregulation and Gerontology’s cytomedine program and studied extensively by Vladimir Khavinson’s research group. Representing the thymus component of the cytomedine bioregulator class, Thymalin’s published research examines its immunomodulatory effects on T-cell differentiation, thymic hormone biology, and aging-associated immune decline. It has been studied in both animal models and clinical settings in Russia, with published literature spanning immune function, longevity biology, and hematopoietic system research.

### What It Is

Thymalin is a polypeptide fraction isolated from bovine (calf) thymus tissue, containing a mixture of short peptide bioregulators in the 1,000–10,000 Da range. Unlike chemically defined single-sequence peptides, thymalin is characterized by its biological activity profile rather than a single molecular formula. Key active components identified in the Khavinson research program include dipeptides Lys-Glu and Glu-Trp. MW range: 1–10 kDa. CAS number associated with the polypeptide complex: 58929-31-0.

### Key Research Applications

- Thymic peptide bioregulator immunomodulation and T-lymphocyte differentiation research
- CD4+ and CD8+ T-cell subset activation and maturation studies
- Age-related thymic involution and immune senescence modeling
- NK cell activity and innate immune function research in aged animal models
- Longevity biology — immune function restoration in aged rodent and primate studies
- Hematopoietic progenitor cell research and bone marrow function studies
- Comparative cytomedine research alongside Epithalon, Pinealon, and other bioregulators
- Thymosin class peptide comparative pharmacology and immunological endpoint studies

### Technical Specifications

| Type | Thymus-derived polypeptide bioregulator |
| --- | --- |
| Molecular Weight | 1–10 kDa (polypeptide mixture) |
| CAS Number | 58929-31-0 |
| Classification | Cytomedine (thymus origin) |
| Purity | ≥95% (biological activity-verified preparation) |
| Form | Lyophilized powder |
| Vial Size | 10mg |
| Storage | −4 °F long-term |

**FOR RESEARCH USE ONLY.** Not intended for human or veterinary consumption, medical diagnosis, treatment, or prevention of any disease or condition. This product has not been evaluated by the FDA or any regulatory agency. Must be handled by qualified research personnel in a compliant laboratory setting. These statements have not been evaluated by the Food and Drug Administration.

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