15% OFF Tesamorelin – 10mg/vial (Research Use Only)
Growth hormone–releasing hormone (GHRH) analog peptide studied in visceral adipose tissue research.
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3–4 vials — 5% off · 5–9 vials — 10% off · 10+ vials — 15% off
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Overview
Tesamorelin is a full-length synthetic analogue of endogenous growth hormone-releasing hormone (GHRH) consisting of the complete 44-amino acid GHRH sequence with a trans-3-hexenoic acid modification at the N-terminus that confers improved proteolytic stability. As the only FDA-approved GHRH analogue (approved as Egrifta for HIV-associated lipodystrophy), tesamorelin offers researchers both an extensive published clinical pharmacology literature and a robust preclinical dataset, making it the reference compound for GHRH biology in tissue-specific GH secretion and metabolic research.
What It Is
Tesamorelin is a 44-amino acid GHRH analogue (identical to human GHRH(1-44)) with a trans-3-hexenoic acid group conjugated at the N-terminal amino group, providing DPP-IV resistance. Molecular weight: approximately 5,135 Da. CAS number: 218949-48-5. Tesamorelin acts as a full agonist at the GHRH receptor (GHRHR), stimulating pulsatile GH release from anterior pituitary somatotrophs.
Key Research Applications
- Full-length GHRH receptor agonism and downstream GH secretion kinetics research
- Pituitary somatotroph physiology and GHRHR signaling pathway studies
- GH pulsatility and IGF-1 axis response modeling in animal and clinical pharmacology
- Visceral adipose tissue biology and adipogenesis/lipolysis regulation research
- Comparative GHRH analogue pharmacology (tesamorelin vs. CJC-1295, Mod GRF 1-29)
- HIV-associated lipodystrophy mechanistic and pharmacological modeling research
- Metabolic syndrome, insulin sensitivity, and GH deficiency model studies
- N-terminal peptide stabilization and DPP-IV resistance research in peptide chemistry
Technical Specifications
| Amino Acids | 44 (full-length GHRH with N-terminal modification) |
| Molecular Weight | ~5,135 Da |
| CAS Number | 218949-48-5 |
| Mechanism | Full GHRH Receptor Agonist |
| Purity | ≥98% (supplier specification) |
| Form | Lyophilized powder |
| Vial Size | 10mg |
| Storage | −4 °F long-term |
FOR RESEARCH USE ONLY. Not intended for human or veterinary consumption, medical diagnosis, treatment, or prevention of any disease or condition. This product has not been evaluated by the FDA or any regulatory agency. Must be handled by qualified research personnel in a compliant laboratory setting. These statements have not been evaluated by the Food and Drug Administration.
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- Temperature handling: Cold-chain packaging available on request for lyophilized peptides
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- Store lyophilized (dry) peptides at −4 °F for long-term stability
- Protect from light and moisture at all times
- Do not freeze
- Where the Storage row in the product specification above differs, follow the specification
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