15% OFF VIP – 10mg/vial (Research Use Only)
Vasoactive intestinal peptide (VIP), a 28-amino-acid neuropeptide studied in neuropeptide, circadian and neuroimmune research. Supplied for laboratory research and identification purposes only.
Availability: In stock
3–4 vials — 5% off · 5–9 vials — 10% off · 10+ vials — 15% off
Applied automatically in the cart. Combines with a discount code up to 20% off in total, and stacks on top of the subscription discount.
Research Disclaimer: All products currently listed on this site are for research purposes only.
Overview
Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide with one of the broadest tissue distribution profiles of any signaling peptide in mammalian biology. Originally isolated from the small intestine but subsequently found throughout the central and peripheral nervous systems, immune tissues, lungs, pancreas, and cardiovascular system, VIP acts on two G-protein coupled receptors (VPAC1 and VPAC2) to produce potent vasodilatory, immunomodulatory, and neuroprotective effects.
What It Is
VIP is a 28-amino acid neuropeptide of the glucagon/secretin superfamily with MW ~3,326 Da, CAS number 37221-79-7. It is equipotent at VPAC1 and VPAC2 receptors, which couple primarily to adenylyl cyclase/cAMP signaling. VIP is co-released with acetylcholine in autonomic neurons and plays major roles in non-adrenergic non-cholinergic (NANC) neurotransmission.
Key Research Applications
- VPAC1 and VPAC2 receptor binding, cAMP signaling, and downstream pathway studies
- Pulmonary vasodilation, airway smooth muscle relaxation, and bronchoprotection research
- Neuroinflammation and microglial activation modulation research
- Immunomodulatory research — T-cell, macrophage, and dendritic cell activity studies
- Circadian rhythm regulation and suprachiasmatic nucleus (SCN) VIP signaling research
- Pancreatic exocrine and endocrine secretion (insulin, glucagon) modulation studies
- Gastrointestinal motility, NANC neurotransmission, and enteric nervous system research
- Neuroprotection and anti-inflammatory mechanism studies in CNS disease models
Technical Specifications
| Amino Acids | 28 |
| Molecular Weight | ~3,326 Da |
| CAS Number | 37221-79-7 |
| Mechanism | VPAC1 / VPAC2 Receptor Agonist (cAMP-mediated) |
| Purity | ≥98% (supplier specification) |
| Form | Lyophilized powder |
| Vial Size | 10mg |
| Storage | −4 °F long-term |
FOR RESEARCH USE ONLY. Not intended for human or veterinary consumption, medical diagnosis, treatment, or prevention of any disease or condition. This product has not been evaluated by the FDA or any regulatory agency. Must be handled by qualified research personnel in a compliant laboratory setting. These statements have not been evaluated by the Food and Drug Administration.
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- Processing: Orders ship within 1–2 business days
- Domestic delivery: 3–5 business days via USPS Priority / UPS Ground
- Free shipping on orders over $100
- Temperature handling: Cold-chain packaging available on request for lyophilized peptides
- Tracking: Emailed automatically at time of dispatch
- Store lyophilized (dry) peptides at −4 °F for long-term stability
- Protect from light and moisture at all times
- Do not freeze
- Where the Storage row in the product specification above differs, follow the specification
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